Ozek Dilay, Karaca Emine Esra, Evren Kemer Ozlem
Associate Professor, Department of Ophthalmology, Ankara City Hospital, Dumlupinar Bulvari 364/B D.24 Etimesgut, Ankara, Turkey.
Department of Ophthalmology, Ankara City Hospital, Ankara, Turkey.
Ther Adv Ophthalmol. 2020 Nov 2;12:2515841420930876. doi: 10.1177/2515841420930876. eCollection 2020 Jan-Dec.
The aim of this study was to evaluate conjunctivochalasis (CCH) and its relationship with tear meniscus and tear function in an elderly population.
This prospective, observational study included 144 eyes of 144 patients aged >65 years who were referred to our clinic for various reasons. The patients were separated into group 1 including 64 eyes of 64 patients with CCH and group 2 including 80 eyes of 80 patients without CCH. All patients in both groups underwent a full ophthalmological examination, and the presence of CCH, fluorescein tear break-up time (FTBUT) test, Schirmer test, ocular surface staining (Oxford grading score) and OSDI (Ocular Surface Disease Index) test results were recorded. Measurements of the conjunctivochalasis area (CCHA), tear meniscus height (TMH) and tear meniscus area (TMA) were taken using anterior segment optic coherence tomography (AS-OCT).
Group 1 comprised 34 females and 30 males with a mean age of 71.15 ± 12.34 years. Group 2 comprised 43 females and 37 males with a mean age of 68.16 ± 6.05 years ( = 0.122). The CCH rate was 44.4% in all of the examined patients. The OSDI score and the ocular surface staining test were significantly higher ( < 0.05), and the FTBUT, TMH and TMA were significantly lower ( < 0.05) in group 1 than in group 2. The Schirmer I test results were not significantly different between the two groups.
The prevalence of CCH is quite high in elderly individuals and may disrupt tear function in these patients.
本研究旨在评估老年人群中的结膜松弛症（CCH）及其与泪液弯月面和泪液功能的关系。
这项前瞻性观察性研究纳入了144例年龄>65岁因各种原因转诊至我们诊所的患者的144只眼睛。患者被分为两组，第1组包括64例患有CCH的患者的64只眼睛，第2组包括80例无CCH的患者的80只眼睛。两组所有患者均接受了全面的眼科检查，并记录了CCH的存在情况、荧光素泪膜破裂时间（FTBUT）试验、泪液分泌试验、眼表染色（牛津分级评分）和眼表疾病指数（OSDI）试验结果。使用眼前节光学相干断层扫描（AS-OCT）测量结膜松弛症面积（CCHA）、泪液弯月面高度（TMH）和泪液弯月面面积（TMA）。
第1组包括34名女性和30名男性，平均年龄为71.15±12.34岁。第2组包括43名女性和37名男性，平均年龄为68.16±6.05岁（P = 0.122）。所有受检患者的CCH发生率为44.4%。第1组的OSDI评分和眼表染色试验显著更高（P<0.05），而FTBUT、TMH和TMA显著更低（P<0.05）。两组之间的泪液分泌试验I结果无显著差异。
CCH在老年人中的患病率相当高，可能会破坏这些患者的泪液功能。
