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T cell receptor-gamma and -delta genes preferentially utilized by adult thymocytes for the surface expression.成年胸腺细胞优先用于表面表达的T细胞受体γ和δ基因。
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An innate-like Vδ1 γδ T cell compartment in the human breast is associated with remission in triple-negative breast cancer.人类乳腺中一种固有样Vδ1 γδ T细胞区室与三阴性乳腺癌的缓解相关。
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Epidermal T lymphocytes--ontogeny, features and function.表皮T淋巴细胞——个体发育、特征与功能
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A T-cell receptor gamma delta-specific monoclonal antibody detects a V gamma 5 region polymorphism.
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T cells expressing the gamma delta T-cell receptor potentiate coxsackievirus B3-induced myocarditis.表达γδ T细胞受体的T细胞增强柯萨奇病毒B3诱导的心肌炎。
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本文引用的文献

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Peptide sequences of T-cell receptor delta and gamma chains are identical to predicted X and gamma proteins.T细胞受体δ链和γ链的肽序列与预测的X蛋白和γ蛋白相同。
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2
Peripheral murine CD3+, CD4-, CD8- T lymphocytes express novel T cell receptor gamma delta structures.外周小鼠CD3 +、CD4 -、CD8 - T淋巴细胞表达新型T细胞受体γδ结构。
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Identification of a monoclonal antibody specific for a murine T3 polypeptide.一种针对小鼠T3多肽的单克隆抗体的鉴定。
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Cell. 1988 Dec 2;55(5):837-47. doi: 10.1016/0092-8674(88)90139-0.
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Monoclonal antibodies specific to native murine T-cell receptor gamma delta: analysis of gamma delta T cells during thymic ontogeny and in peripheral lymphoid organs.针对天然小鼠T细胞受体γδ的单克隆抗体:胸腺发育过程中和外周淋巴器官中γδ T细胞的分析
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T cell receptor-gamma and -delta genes preferentially utilized by adult thymocytes for the surface expression.成年胸腺细胞优先用于表面表达的T细胞受体γ和δ基因。
J Immunol. 1989 Mar 15;142(6):2112-21.
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Two better cell lines for making hybridomas expressing specific T cell receptors.两种更适合用于制备表达特异性T细胞受体的杂交瘤的细胞系。
J Immunol. 1989 Sep 15;143(6):1822-5.
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Limited receptor repertoire in a mycobacteria-reactive subset of gamma delta T lymphocytes.γδ T淋巴细胞的分枝杆菌反应性子集中受体库有限。
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Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining.T细胞受体γδ基因的连接序列:对γδ T细胞谱系及V-(D)-J连接新中间体的影响
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10
Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function.上皮内淋巴细胞。解剖部位而非T细胞受体形式决定其表型和功能。
J Exp Med. 1989 Nov 1;170(5):1569-81. doi: 10.1084/jem.170.5.1569.

泌乳期乳腺淋巴细胞上γ/δ T细胞受体的表达

Expression of gamma/delta T cell receptors on lymphocytes from the lactating mammary gland.

作者信息

Reardon C, Lefrancois L, Farr A, Kubo R, O'Brien R, Born W

机构信息

Department of Dermatology, University of Colorado Health Sciences Center, Denver 80262.

出版信息

J Exp Med. 1990 Oct 1;172(4):1263-6. doi: 10.1084/jem.172.4.1263.

DOI:10.1084/jem.172.4.1263
PMID:2145390
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2188620/
Abstract

gamma/delta cells were at least four times more frequent in lactating mouse mammary glands than among T cells of the most proximal lymph nodes. Two-color staining of freshly isolated T cells and a study of clonally expressed gamma/delta receptors on hybridomas further revealed that the mammary gamma/delta population is heterogeneous, including at least three different subsets, among them cells expressing V gamma 5, V gamma 4 together with V delta 4, or none of these V regions.

摘要

在泌乳小鼠乳腺中,γ/δ细胞的数量至少是最接近的淋巴结T细胞数量的四倍。对新鲜分离的T细胞进行双色染色以及对杂交瘤上克隆表达的γ/δ受体进行研究进一步表明,乳腺γ/δ细胞群体是异质性的,包括至少三个不同的亚群,其中有表达Vγ5、Vγ4和Vδ4的细胞,或不表达这些V区的细胞。