深度镇静是否会影响无导管 pH 检测 48 小时的结果？
Does deep sedation impact the results of 48 hours catheterless pH testing?
机构信息
Department of Gastroenterology and Hepatology, Winthrop University Hospital, Mineola, NY 11501, USA.
出版信息
World J Gastroenterol. 2011 Mar 14;17(10):1304-7. doi: 10.3748/wjg.v17.i10.1304.
AIM
To study a cohort of patients undergoing 48 h Bravo pH testing receiving deep sedation with propofol.
METHODS
We retrospectively reviewed the charts of 197 patients (81 male, 116 female) who underwent Bravo esophageal pH monitoring from July 2003 to January 2008. All patients underwent Bravo pH probe placement via esophagogastroduodenoscopy (EGD) and received propofol for sedation. Patients on a proton pump inhibitor (89 patients) were excluded. Acid reflux variables measured included the total, upright, and supine fractions of time at pH < 4 and DeMeester score, and were compared between day 1 and day 2.
RESULTS
Of the 108 patients that were included in the study, the most common indication for Bravo pH monitoring was heartburn, with chest pain being the second most common. A signed rank test revealed no statistically significant difference between day 1 and day 2 reflux episodes.
CONCLUSION
Patients who received propofol for sedation for EGD with Bravo pH capsule placement did not experience any significant difference in reflux episodes from day 1 to day 2.
目的
研究一组接受 48 小时 Bravo pH 测试并接受异丙酚深度镇静的患者。
方法
我们回顾性分析了 2003 年 7 月至 2008 年 1 月期间接受 Bravo 食管 pH 监测的 197 例患者（81 例男性，116 例女性）的病历。所有患者均通过食管胃十二指肠镜（EGD）进行 Bravo pH 探头放置，并接受异丙酚镇静。排除质子泵抑制剂（89 例）患者。测量的酸反流变量包括 pH<4 的时间的总、直立和仰卧部分以及 DeMeester 评分，并在第 1 天和第 2 天进行比较。
结果
在纳入研究的 108 例患者中，进行 Bravo pH 监测的最常见指征是烧心，胸痛是第二常见指征。符号秩检验显示第 1 天和第 2 天反流发作之间无统计学差异。
结论
接受异丙酚镇静的患者在接受 EGD 和 Bravo pH 胶囊放置时，从第 1 天到第 2 天的反流发作没有明显差异。
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