Dept of Human Anatomy, University of Nairobi, P.O. Box 25361-00603, Nairobi, Kenya.
J Craniomaxillofac Surg. 2012 Feb;40(2):e39-45. doi: 10.1016/j.jcms.2011.03.011. Epub 2011 Mar 31.
Ameloblastoma presenting in the adolescent age group is rare with few studies documenting their occurrence.
The aim of this study was to carry out an analysis of the pattern and occurrence of ameloblastoma in those less than 20 years of age.
Patients from the University of Nairobi Dental teaching Hospital treated for ameloblastoma were included in the study over a 13-year period. The study highlights the demographic, clinic-radiographic and histologic features of benign locally aggressive lesions.
A total of 127 patients were recorded of which, 27 (21.3%) were below the age of 20 years; no case was reported below the age of 10 years. 18.5% were below the age of 14 years and 81.5% were 15-19 years old. The gender predilection was ∼1:1. All of the tumours occurred in the mandible, with radiographic features of a multilocular radiolucencies (85.2%); and a fewer unilocular lesions (14.8%). The management is in a staged-wise approach: resection and/or disarticulation with temporary reconstruction using mandibular stainless steel or titanium plates and delayed bone grafting.
The occurrence of ameloblastoma can mimic an odontogenic cyst, clinicians therefore need to be vigilant when examining adolescents so that conservative treatment is started early in order to reduce the subsequent morbidity.
青少年时期发生的成釉细胞瘤较为罕见,仅有少数研究记录了其发生情况。
本研究旨在分析 20 岁以下成釉细胞瘤的发病模式和发病情况。
对 13 年间在肯尼亚内罗毕大学牙科学院附属医院接受成釉细胞瘤治疗的患者进行了研究。本研究强调了良性局部侵袭性病变的人口统计学、临床-影像学和组织学特征。
共记录了 127 例患者,其中 27 例(21.3%)年龄小于 20 岁;没有 10 岁以下的病例报告。18.5%的患者年龄在 14 岁以下,81.5%的患者年龄在 15-19 岁之间。性别偏好约为 1:1。所有肿瘤均发生在下颌骨,影像学特征为多房性透光区(85.2%);而较少出现单房性病变(14.8%)。治疗采用分阶段方法:切除和/或关节离断,临时重建采用下颌不锈钢或钛板,并延迟骨移植。
成釉细胞瘤的发生可模拟牙源性囊肿,因此临床医生在检查青少年时需要保持警惕,以便尽早开始保守治疗,从而降低后续发病率。