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儿童颌骨造釉细胞瘤:尼日利亚东南部一家三级医院的病例评估。

Ameloblastoma of the jaws in children: an evaluation of cases seen in a tertiary hospital in South-Eastern Nigeria.

机构信息

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, College of Medicine, University of Nigeria, Ituku- Ozalla, Enugu, Nigeria.

Department of Otorhinolaryngology, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Ituku- Ozalla, Enugu, Nigeria.

出版信息

Ghana Med J. 2020 Mar;54(1):36-41. doi: 10.4314/gmj.v54i1.6.

Abstract

BACKGROUND

Ameloblastoma is one of the most common benign odontogenic tumours in Nigeria. It is considered uncommon in children.

MATERIALS AND METHODS

This is a retrospective study of pediatric patients with histopathological diagnosis of ameloblastoma seen over seven years at the Oral and Maxillofacial Surgery Department of the University of Nigeria Teaching Hospital, Enugu, Nigeria. Relevant information was retrieved from patients' records and data obtained were analysed using SPSS version 23, the chi-square test was used to compare qualitative variables, a p-value of <0.05 was considered as significant.

RESULTS

One hundred and thirty-six cases of ameloblastoma in all age groups were seen within the period. Thirty of the cases met the requirement. The mean age of the patients was 14.4 STD 2.03 (range from 10-17) years. Fourteen (46.7%) patients were male while 16 (53.3%) were female giving a ratio of 1:1.1. The duration of the lesion ranged from 3 months to 72 months (mean 15.07 months). Histologically, the follicular type (n=20, 66.7%) constitute the majority, while the clinical types were solid-multicystic (n=18, 60%) and unicystic (n=12, 40%). Enucleation was the treatment of choice in most (n=18, (60%)) of the patients.

CONCLUSION

Ameloblastoma is relatively uncommon in children, especially those less than ten years of age. The solid-multicystic variety was the predominant type in the children studied. Most patients presented long after the onset of the tumour and enucleation with mechanical curettage produced satisfactory results in these patients.

FUNDING

None declared.

摘要

背景

成釉细胞瘤是尼日利亚最常见的良性牙源性肿瘤之一。它在儿童中较为少见。

材料和方法

这是一项回顾性研究,研究对象为在尼日利亚恩古尼大学教学医院口腔颌面外科就诊的 7 年内经组织病理学诊断为成釉细胞瘤的儿科患者。从患者的病历中检索到相关信息,使用 SPSS 版本 23 分析获得的数据,使用卡方检验比较定性变量,p 值<0.05 被认为具有统计学意义。

结果

在所研究的时间段内,所有年龄段的成釉细胞瘤患者共有 136 例,其中符合要求的有 30 例。患者的平均年龄为 14.4±2.03 岁(范围为 10-17 岁)。14 例(46.7%)为男性,16 例(53.3%)为女性,男女比例为 1:1.1。病变持续时间从 3 个月到 72 个月不等(平均 15.07 个月)。组织学上,滤泡型(n=20,66.7%)占多数,而临床类型为实性-多囊型(n=18,60%)和单囊型(n=12,40%)。大多数患者(n=18,60%)选择的治疗方法是肿瘤切除术。

结论

成釉细胞瘤在儿童中相对少见,尤其是 10 岁以下的儿童。在本研究中,实性-多囊型是最常见的类型。大多数患者在肿瘤发病后很长时间才就诊,肿瘤切除术联合机械刮除术为这些患者带来了满意的效果。

经费

无。

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本文引用的文献

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Biological profile of ameloblastoma and its location in the jaw in 1246 Nigerians.1246 例尼日利亚人口腔造釉细胞瘤的生物学特征及其在颌骨中的分布。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Nov;126(5):424-431. doi: 10.1016/j.oooo.2018.06.014. Epub 2018 Jul 24.
3
Ameloblastoma: a clinical review and trends in management.成釉细胞瘤:临床综述与治疗趋势
Eur Arch Otorhinolaryngol. 2016 Jul;273(7):1649-61. doi: 10.1007/s00405-015-3631-8. Epub 2015 Apr 30.
6
Treatment of ameloblastoma of the jaws in children.儿童颌骨成釉细胞瘤的治疗
Ghana Med J. 2011 Mar;45(1):35-7. doi: 10.4314/gmj.v45i1.68921.
9
Ameloblastoma in children and adolescents.儿童和青少年的成釉细胞瘤
Br J Oral Maxillofac Surg. 2010 Oct;48(7):549-54. doi: 10.1016/j.bjoms.2009.08.020. Epub 2009 Sep 24.
10
Surgical management of ameloblastoma in children.儿童成釉细胞瘤的外科治疗
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Oct;104(4):478-85. doi: 10.1016/j.tripleo.2007.01.033. Epub 2007 May 24.

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