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本文引用的文献

1
Cholangiocyte myosin IIB is required for localized aggregation of sodium glucose cotransporter 1 to sites of Cryptosporidium parvum cellular invasion and facilitates parasite internalization.胆管细胞肌球蛋白 IIB 对于钠葡萄糖协同转运蛋白 1 局部聚集到隐孢子虫细胞入侵部位以及促进寄生虫内化是必需的。
Infect Immun. 2010 Jul;78(7):2927-36. doi: 10.1128/IAI.00077-10. Epub 2010 May 10.
2
NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responses.微小 RNA 基因在微小隐孢子虫感染后受 NF-κB p65 依赖性反式激活，从而刺激上皮细胞免疫应答。
PLoS Pathog. 2009 Dec;5(12):e1000681. doi: 10.1371/journal.ppat.1000681. Epub 2009 Dec 4.
3
MicroRNA-98 and let-7 confer cholangiocyte expression of cytokine-inducible Src homology 2-containing protein in response to microbial challenge.微小RNA-98和let-7在应对微生物挑战时赋予胆管细胞细胞因子诱导含Src同源2蛋白的表达。
J Immunol. 2009 Aug 1;183(3):1617-24. doi: 10.4049/jimmunol.0804362. Epub 2009 Jul 10.
4
Cryptosporidium: genomic and biochemical features.隐孢子虫：基因组和生化特征。
Exp Parasitol. 2010 Jan;124(1):2-9. doi: 10.1016/j.exppara.2008.12.014. Epub 2008 Dec 31.
5
Role of CpSUB1, a subtilisin-like protease, in Cryptosporidium parvum infection in vitro.类枯草杆菌蛋白酶CpSUB1在微小隐孢子虫体外感染中的作用
Eukaryot Cell. 2009 Apr;8(4):470-7. doi: 10.1128/EC.00306-08. Epub 2009 Jan 23.
6
Polymorphic mucin antigens CpMuc4 and CpMuc5 are integral to Cryptosporidium parvum infection in vitro.多态性粘蛋白抗原CpMuc4和CpMuc5是微小隐孢子虫体外感染所必需的。
Eukaryot Cell. 2009 Apr;8(4):461-9. doi: 10.1128/EC.00305-08. Epub 2009 Jan 23.
7
Cryptosporidium infection of human intestinal epithelial cells increases expression of osteoprotegerin: a novel mechanism for evasion of host defenses.人肠道上皮细胞的隐孢子虫感染会增加骨保护素的表达：一种逃避宿主防御的新机制。
J Infect Dis. 2008 Mar 15;197(6):916-23. doi: 10.1086/528374.
8
SGLT-1-mediated glucose uptake protects human intestinal epithelial cells against Giardia duodenalis-induced apoptosis.SGLT-1介导的葡萄糖摄取可保护人肠上皮细胞免受十二指肠贾第鞭毛虫诱导的凋亡。
Int J Parasitol. 2008 Jul;38(8-9):923-34. doi: 10.1016/j.ijpara.2007.12.004. Epub 2008 Jan 17.
9
Cryptosporidium p30, a galactose/N-acetylgalactosamine-specific lectin, mediates infection in vitro.隐孢子虫p30是一种半乳糖/N-乙酰半乳糖胺特异性凝集素，可在体外介导感染。
J Biol Chem. 2007 Nov 30;282(48):34877-87. doi: 10.1074/jbc.M706950200. Epub 2007 Sep 28.
10
A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection.一种细胞微小RNA，即let-7i，可调节Toll样受体4的表达，并有助于胆管细胞针对微小隐孢子虫感染的免疫反应。
J Biol Chem. 2007 Sep 28;282(39):28929-28938. doi: 10.1074/jbc.M702633200. Epub 2007 Jul 27.

隐孢子虫感染的细胞生物学。

The cell biology of cryptosporidium infection.

机构信息

Center for Basic Research in Digestive Diseases, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

出版信息

Microbes Infect. 2011 Aug;13(8-9):721-30. doi: 10.1016/j.micinf.2011.03.008. Epub 2011 Mar 31.

DOI:10.1016/j.micinf.2011.03.008
PMID:21458585
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3130844/
Abstract

Cryptosporidiosis remains a significant cause of enteric disease worldwide. Basic investigations of host: pathogen interactions have revealed the intricate processes mediating infection. The following summarizes the interactions that mediate infection and the host responses that both permit and ultimately clear the infection.

摘要

隐孢子虫病仍然是全世界肠道疾病的一个重要病因。对宿主-病原体相互作用的基础研究揭示了介导感染的复杂过程。以下总结了介导感染的相互作用以及既允许又最终清除感染的宿主反应。