Department of Experimental and Diagnostic Medicine, University of Ferrara, Ferrara, Italy.
Dig Liver Dis. 2011 Mar;43 Suppl 4:S344-55. doi: 10.1016/S1590-8658(11)60590-2.
Epithelial colorectal tumors are common pathologic entities. Their histology report should be comprehensive of a series of pathologic parameters essential for the correct clinical management of the patients. Diagnostic histologic criteria of adenomatous, serrated, inflammatory, and hamartomatous polyps and of polyposis syndromes are discussed. In addition, the pathologic features of early and advanced colorectal cancer are described and a checklist is given. Finally, molecular prognostic and predictive factors currently employed in the treatment of colorectal cancer are discussed.
上皮性结直肠肿瘤是常见的病理实体。其组织学报告应包括一系列对于患者正确临床管理至关重要的病理参数。讨论了腺瘤性、锯齿状、炎症性和错构瘤性息肉以及息肉病综合征的诊断组织学标准。此外,还描述了早期和晚期结直肠癌的病理特征,并提供了一个检查表。最后,讨论了目前在结直肠癌治疗中使用的分子预后和预测因素。