Los Angeles and Sherman Oaks, Calif. From the Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Southern California; Cedars-Sinai Hospital; and the Grossman Burn Center.
Plast Reconstr Surg. 2011 Apr;127(4):1593-1599. doi: 10.1097/PRS.0b013e31820a6511.
Contracture deformities of the upper extremity are encountered frequently in burn victims. Surgical repair of this problem is challenged by a paucity of soft tissue, poor functional outcome, and a high rate of recurrence. Acellular dermal matrix has become increasingly popular in reconstructive surgery--at times--as an alternative to local and free tissue transfer in different parts of the body. However, its applicability in contracture release, particularly in hand surgery, has not been widely explored.
Nine patients with burn contracture scars involving different locations in the hand and the wrist underwent two-stage reconstruction consisting of contracture release and use of acellular dermal matrix followed by definitive coverage with skin graft at the second stage. Patients were followed up for a period of at least 10 months (range, 10 to 25 months), during which time the passive range of motion of the hand was used as a quantitative measure of surgical outcome.
All nine patients retained at least 83 percent of the corrected range of motion involving the affected joints by 1 year and at least 89 percent of correction at each webspace. No patient required a revision procedure.
Acellular dermal matrix can be an effective tool in surgical treatment of difficult burn contracture deformity in the hand, with lasting results.
上肢挛缩畸形在烧伤患者中较为常见。由于软组织不足、功能预后不良和高复发率,手术修复这一问题具有挑战性。脱细胞真皮基质在重建外科中越来越受欢迎——有时——作为身体不同部位局部和游离组织转移的替代物。然而,其在挛缩松解中的适用性,特别是在手外科中,尚未得到广泛探索。
9 例手部和腕部不同部位烧伤挛缩瘢痕患者接受了两阶段重建,包括挛缩松解和使用脱细胞真皮基质,然后在第二阶段用皮片进行确定性覆盖。患者随访至少 10 个月(范围 10 至 25 个月),在此期间,手部的被动活动范围用作手术结果的定量测量。
所有 9 例患者在 1 年内至少保留了受累关节纠正活动范围的 83%,每个蹼间空间至少保留了 89%的纠正。没有患者需要进行修正手术。
脱细胞真皮基质在手外科治疗困难性烧伤挛缩畸形中是一种有效的工具,可获得持久的效果。