De Simone Clara, Caldarola Giacomo, D'Agostino Magda, Carbone Angelo, Guerriero Cristina, Bonomo Lorenzo, Amerio Pierluigi, Magarelli Nicola
Department of Dermatology, Catholic University of the Sacred Heart, Rome, Italy.
Clin Dev Immunol. 2011;2011:390726. doi: 10.1155/2011/390726. Epub 2011 Feb 8.
Given that clinical evaluation may underestimate the joint damage and that early treatment can slow down psoriatic arthritis (PsA) progression, screening psoriasis patients with imaging tools that can depict early PsA changes would entail clear benefits.
To compare the ability of X-ray and ultrasound (US) examination in detecting morphological abnormalities consistent with early PsA in patients with psoriasis, using rheumatological evaluation as the gold standard for diagnosis.
Patients with chronic plaque psoriasis and no previous PsA diagnosis attending our outpatient dermatology clinic and reporting finger/toe joint and/or tendon pain underwent X-ray and US evaluation; they were subsequently referred to a rheumatologist for clinical examination and review of imaging findings.
Abnormal US and/or X-ray findings involving at least one finger and/or toe (joints and/or tendons) were seen in 36/52 patients: 11 had one or more X-ray abnormalities, including erosion, joint space narrowing, new bone formation, periarticular soft tissue swelling, and periarticular osteoporosis; 36 had suspicious changes on US.
US proved valuable in detecting joint and/or tendon abnormalities in the fingers and toes of patients with suspicious changes. The dermatologist should consider US to obtain an accurate assessment of suspicious findings.
鉴于临床评估可能低估关节损伤,且早期治疗可减缓银屑病关节炎(PsA)的进展,使用能够描绘早期PsA变化的成像工具对银屑病患者进行筛查将带来明显益处。
以风湿病学评估作为诊断的金标准,比较X线和超声(US)检查在检测银屑病患者中与早期PsA一致的形态学异常方面的能力。
在我们皮肤科门诊就诊、患有慢性斑块状银屑病且既往无PsA诊断、报告手指/脚趾关节和/或肌腱疼痛的患者接受了X线和US评估;随后他们被转诊至风湿病学家处进行临床检查并复查影像学检查结果。
52例患者中有36例出现累及至少一个手指和/或脚趾(关节和/或肌腱)的异常US和/或X线表现:11例有一项或多项X线异常,包括侵蚀、关节间隙变窄、新骨形成、关节周围软组织肿胀和关节周围骨质疏松;36例在US检查中有可疑变化。
超声在检测有可疑变化的患者手指和脚趾的关节和/或肌腱异常方面被证明具有价值。皮肤科医生应考虑使用超声来准确评估可疑发现。