Institute of Virology, University of Cologne, Fürst-Pückler-Strasse 56, 50935 Cologne, Germany.
Med Microbiol Immunol. 2011 Nov;200(4):219-23. doi: 10.1007/s00430-011-0193-2. Epub 2011 Apr 2.
The high number of Turkish immigrants in the German state North-Rhine Westphalia (NRW) compelled us to look for HIV-infected patients with Turkish nationality. In the AREVIR database, we found 127 (107 men, 20 women) Turkish HIV patients living in NRW. In order to investigate transmission clusters and their correlation to gender, nationality and self-reported transmission mode, a phylogenetic analysis including pol gene sequences was performed. Subtype distribution and the number of HIV drug resistance mutations in the Turkish patient group were found to be similar to the proportion in the non-Turkish patients. Great differences were observed in self-reported mode of transmission in the heterosexual Turkish male subgroup. Neighbour-joining tree of pol gene sequences gave indication that 59% of these reported heterosexual transmissions cluster with those of men having sex with men in the database. This is the first study analysing HIV type distribution, drug resistance mutations and transmission mode in a Turkish immigrant population.
德国北莱茵-威斯特法伦州（NRW）有大量土耳其移民，这促使我们寻找具有土耳其国籍的 HIV 感染者。在 AREVIR 数据库中，我们发现了 127 名（107 名男性，20 名女性）居住在 NRW 的土耳其 HIV 患者。为了调查传播集群及其与性别、国籍和自我报告的传播模式的相关性，进行了包括 pol 基因序列在内的系统发育分析。在土耳其患者组中发现，亚型分布和 HIV 耐药突变的数量与非土耳其患者的比例相似。在异性恋土耳其男性亚组中，自我报告的传播模式存在很大差异。pol 基因序列的邻接法树表明，这些报告的异性传播中有 59%与数据库中与男性发生性关系的男性的传播集群在一起。这是第一项分析土耳其移民人群中 HIV 类型分布、耐药突变和传播模式的研究。
