Calhoun Cardiology Center, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT 06030-3944, USA.
Exp Clin Psychopharmacol. 2011 Apr;19(2):173-81. doi: 10.1037/a0023031.
As the American population ages, older adults are accounting for a larger percentage of the drug-abusing population, but little attention has been given to this age group especially in regards to evaluating responsivity to different treatment modalities. Contingency management (CM) is a highly effective behavioral treatment that provides positive tangible reinforcers for objective evidence of behavior change. The purpose of this study was to examine main and interactive effects of age on outcomes in cocaine-dependent patients receiving CM with standard care (SC) or SC alone. Patients (N = 393) participating in 1 of 3 randomized trials of CM for cocaine dependence were divided into young, middle, and older age cohorts. Baseline characteristics and outcomes were compared across the age groups. The oldest age group had more medical problems than the youngest and middle age groups but had fewer legal difficulties and psychiatric symptoms. The oldest age group remained in treatment significantly longer than the other age groups, regardless of the type of treatment received. Although all age groups benefited from CM in terms of retention and longest duration of abstinence achieved, a significant age by treatment interaction effect emerged, with the older cohort improving relatively less from CM than the younger age groups. These findings demonstrate that age may play a role in moderating intervention outcomes, and tailoring CM to the needs of older and middle-aged substance abusers may be important for improving outcomes in this growing population.
随着美国人口老龄化,老年人在滥用药物人群中的比例越来越大,但针对这一年龄群体的关注相对较少,特别是在评估对不同治疗方式的反应方面。条件性管理(CM)是一种非常有效的行为治疗方法,它为行为改变的客观证据提供积极的有形强化。本研究的目的是检验年龄对接受 CM 联合标准护理(SC)或仅接受 SC 的可卡因依赖患者结局的主要和交互影响。参与可卡因依赖 CM 的 3 项随机试验之一的患者(N=393)被分为年轻、中年和老年组。比较了不同年龄组的基线特征和结局。最年长的年龄组比最年轻和中年组有更多的医疗问题,但法律问题和精神症状较少。无论接受何种治疗,最年长的年龄组在治疗中的停留时间明显长于其他年龄组。尽管所有年龄组在保留和最长禁欲时间方面都从 CM 中获益,但出现了显著的年龄与治疗的交互作用,与年轻年龄组相比,年长组从 CM 中获益相对较少。这些发现表明,年龄可能在调节干预结果方面发挥作用,针对年长和中年物质滥用者的需求调整 CM 可能对改善这一不断增长的人群的结果很重要。