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Enhancing the mechanical stability of proteins through a cocktail approach.
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Protein mechanics: from single molecules to functional biomaterials.
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Modulating the mechanical stability of extracellular matrix protein tenascin-C in a controlled and reversible fashion.
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Configurational entropy modulates the mechanical stability of protein GB1.
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Computational and single-molecule force studies of a macro domain protein reveal a key molecular determinant for mechanical stability.
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Mechanical forces and ligand binding modulate PilY1 mechanosensitive protein.
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Mechanism for the Unfolding of the TOP7 Protein in Steered Molecular Dynamics Simulations as Revealed by Mutual Information Analysis.
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A novel strategy for utilizing voice coil servoactuators in tensile tests of low volume protein hydrogels.
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Dual binding of an antibody and a small molecule increases the stability of TERRA G-quadruplex.
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Worm-like Ising model for protein mechanical unfolding under the effect of osmolytes.
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Single-molecule force spectroscopy reveals the individual mechanical unfolding pathways of a surface layer protein.
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本文引用的文献

1
Protein mechanics: from single molecules to functional biomaterials.
Acc Chem Res. 2010 Oct 19;43(10):1331-41. doi: 10.1021/ar100057a.
2
Identification of a mechanical rheostat in the hydrophobic core of protein L.
J Mol Biol. 2009 Oct 16;393(1):237-48. doi: 10.1016/j.jmb.2009.08.015. Epub 2009 Aug 13.
3
On the remarkable mechanostability of scaffoldins and the mechanical clamp motif.
Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13791-6. doi: 10.1073/pnas.0813093106. Epub 2009 Jul 31.
4
The titin-telethonin complex is a directed, superstable molecular bond in the muscle Z-disk.
Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13307-133310. doi: 10.1073/pnas.0902312106. Epub 2009 Jul 21.
5
Modulating the mechanical stability of extracellular matrix protein tenascin-C in a controlled and reversible fashion.
J Mol Biol. 2009 Jul 24;390(4):820-9. doi: 10.1016/j.jmb.2009.05.057. Epub 2009 May 27.
6
Single molecule force spectroscopy reveals engineered metal chelation is a general approach to enhance mechanical stability of proteins.
Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11152-7. doi: 10.1073/pnas.0803446105. Epub 2008 Aug 6.
7
An effective strategy for the design of proteins with enhanced mechanical stability.
Angew Chem Int Ed Engl. 2008;47(36):6900-3. doi: 10.1002/anie.200801761.
8
Protein-protein interaction regulates proteins' mechanical stability.
J Mol Biol. 2008 May 16;378(5):1132-41. doi: 10.1016/j.jmb.2008.03.046. Epub 2008 Mar 28.
9
Mechanical unfoldons as building blocks of maltose-binding protein.
J Mol Biol. 2008 Apr 25;378(2):447-58. doi: 10.1016/j.jmb.2008.02.025. Epub 2008 Feb 21.
10
A functional single-molecule binding assay via force spectroscopy.
Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15677-81. doi: 10.1073/pnas.0705367104. Epub 2007 Sep 25.

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