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[临界性动脉高血压的诊断、自然病程及预后意义的相关问题。II. 临界性动脉高血压的后遗症]

[Selected problems of diagnosis, natural course and prognostic significance of borderline arterial hypertension. II. Sequelae of borderline arterial hypertension].

作者信息

Kawecka-Jaszcz K

机构信息

I Kliniki Kardiologii, IK AM w Krakowie.

出版信息

Przegl Lek. 1990;47(3):323-7.

PMID:2146705
Abstract

In 490 working men, aged 40-59 years the sequelae of borderline arterial hypertension (BH) were evaluated. The patients with BH (n = 253) were matched with normal controls (n = 237). At 13 years the cardiovascular state, ability to work and mortality were assessed. A significantly more frequent incidence of left ventricular hypertrophy and overload was found when hypertension developed. In the group of initial BH less men continued work (36%) than in the control group (48.1%, p less than 0.01), despite the same age. A relation between the ability to work and blood pressure becomes more prominent while taking into account final diagnosis; i.e. 65.7% of actual normotensives, 56.4% of the patients with BH and 47.5% with hypertension continue their work. The mortality rate was higher (15.4%) in the group with BH than in the controls (8.4%, p less than 0.01). The highest death rate was found when BH was combined with other coronary risk factors. The results confirm the presence of both indirect (through the development of arterial hypertension) and harmful effects of BH. They also show the need of devoting special attention to patients with BH and concommitant coronary risk factors.

摘要

对490名年龄在40 - 59岁的在职男性的临界高血压(BH)后遗症进行了评估。将BH患者(n = 253)与正常对照组(n = 237)进行匹配。在13年时,评估了心血管状况、工作能力和死亡率。当高血压发展时,发现左心室肥厚和负荷过重的发生率明显更高。在初始BH组中,继续工作的男性(36%)比对照组(48.1%,p < 0.01)少,尽管年龄相同。在考虑最终诊断时,工作能力与血压之间的关系变得更加显著;即实际血压正常者中有65.7%、BH患者中有56.4%以及高血压患者中有47.5%继续工作。BH组的死亡率(15.4%)高于对照组(8.4%,p < 0.01)。当BH与其他冠心病危险因素并存时,死亡率最高。结果证实了BH既有间接影响(通过动脉高血压的发展),也有有害影响。它们还表明需要特别关注伴有冠心病危险因素的BH患者。

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