Institute for Disorder of Impulse and Attention, School of Psychology, University of Southampton, Southampton, SO17 1BJ, UK.
Expert Rev Neurother. 2011 Apr;11(4):557-63. doi: 10.1586/ern.11.39.
Attention-deficit/hyperactivity disorder (ADHD) is a high-cost/high-burden disorder. Early detection and intervention may prevent or ameliorate the development of the disorder and reduce its long-term impact. In this article, we set out a rationale for an early detection and intervention program. First, we highlight the costs of the condition and second, we discuss the limitations of the current treatments. We then outline the potential value of an early detection and intervention program. We review evidence on predictors of poor outcomes for early ADHD signs and discuss how these might allow us to target early intervention more cost-effectively. We then examine potential barriers to engagement with at-risk samples. This leads to a discussion of possible intervention approaches and how these could be improved. Finally, we describe the Program for Early Detection and Intervention for ADHD (PEDIA), a 5-year program of research supported by the UK National Institute for Health Research and conducted at the University of Southampton (Southampton, UK), which aims to develop and evaluate a strategy for early intervention.
注意缺陷多动障碍（ADHD）是一种高成本/高负担的疾病。早期发现和干预可能预防或改善疾病的发展，并降低其长期影响。在本文中，我们提出了一个早期发现和干预计划的基本原理。首先，我们强调了该疾病的成本，其次，我们讨论了当前治疗方法的局限性。然后，我们概述了早期发现和干预计划的潜在价值。我们回顾了早期 ADHD 症状不良预后的预测因素的证据，并讨论了如何使我们能够更具成本效益地针对早期干预。然后，我们研究了参与高危样本的潜在障碍。这导致了对可能的干预方法的讨论，以及如何改进这些方法。最后，我们描述了注意缺陷多动障碍早期发现和干预计划（PEDIA），这是英国南安普敦大学（英国南安普敦）的一个为期 5 年的研究项目，由英国国家卫生研究院资助，旨在开发和评估一种早期干预策略。
