[蛋白质组学与输血医学]

[Proteomics and transfusion medicine].

作者信息

Lion N, Prudent M, Crettaz D, Tissot J-D

机构信息

Service régional vaudois de transfusion sanguine, 2, route de la Corniche, 1066 Épalinges, Suisse.

出版信息

Transfus Clin Biol. 2011 Apr;18(2):79-96. doi: 10.1016/j.tracli.2011.02.018. Epub 2011 Apr 5.

DOI:10.1016/j.tracli.2011.02.018

PMID:21470892

Abstract

The term "proteomics" covers tools and techniques that are used to analyze and characterize complex mixtures of proteins from various biological samples. In this short review, a typical proteomic approach, related to the study of particular and illustrative situation related to transfusion medicine is reported. This "case report" will allow the reader to be familiar with a practical proteomic approach of a real situation, and will permit to describe the tools that are usually used in proteomic labs, and, in a second part, to present various proteomic applications in transfusion medicine.

摘要

“蛋白质组学”一词涵盖了用于分析和表征来自各种生物样品的复杂蛋白质混合物的工具和技术。在这篇简短的综述中，报告了一种与输血医学中特定且具有说明性情况的研究相关的典型蛋白质组学方法。这个“病例报告”将使读者熟悉实际情况的实用蛋白质组学方法，并将介绍蛋白质组学实验室通常使用的工具，并且在第二部分中展示蛋白质组学在输血医学中的各种应用。