University of Rochester, School of Nursing, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Sleep Med. 2013 Jan;14(1):5-11. doi: 10.1016/j.sleep.2010.12.011. Epub 2011 Apr 5.
Changes in core body temperature due to heat transfer through the skin have a major influence on sleep regulation. Traditional measures of skin temperature are often complicated by extensive wiring and are not practical for use in normal living conditions. This review describes studies examining the reliability, validity and utility of the iButton®, a wireless peripheral thermometry device, in sleep/wake research.
A review was conducted of English language literature on the iButton as a measure of circadian body temperature rhythms associated with the sleep/wake cycle.
Seven studies of the iButtton as a measure of human body temperature were included. The iButton was found to be a reliable and valid measure of body temperature. Its application to human skin was shown to be comfortable and tolerable with no significant adverse reactions. Distal skin temperatures were negatively correlated with sleep/wake activity, and the temperature gradient between the distal and proximal skin (DPG) was identified as an accurate physiological correlate of sleep propensity. Methodological issues included site of data logger placement, temperature masking factors, and temperature data analysis.
The iButton is an inexpensive, wireless data logger that can be used to obtain a valid measurement of human skin temperature. It is a practical alternative to traditional measures of circadian rhythms in sleep/wake research. Further research is needed to determine the utility of the iButton in vulnerable populations, including those with neurodegenerative disorders and memory impairment and pediatric populations.
通过皮肤传热引起的核心体温变化对睡眠调节有重大影响。传统的皮肤温度测量方法通常由于布线复杂而不实用，不适合在正常生活条件下使用。本综述描述了研究人员检查 iButton（一种无线周边测温设备）在睡眠/觉醒研究中的可靠性、有效性和实用性的研究。
对 iButton 作为与睡眠/觉醒周期相关的昼夜节律体温度测量的英语文献进行了综述。
纳入了七项关于 iButton 作为人体温度测量的研究。研究表明，iButton 是一种可靠和有效的体温测量方法。它在人体皮肤上的应用被证明是舒适和耐受的，没有明显的不良反应。远端皮肤温度与睡眠/觉醒活动呈负相关，远端和近端皮肤之间的温度梯度（DPG）被确定为睡眠倾向的准确生理相关物。方法学问题包括数据记录器放置位置、温度掩蔽因素和温度数据分析。
iButton 是一种廉价的无线数据记录器，可以用来获得人体皮肤温度的有效测量。它是睡眠/觉醒研究中昼夜节律传统测量方法的实用替代方法。需要进一步研究确定 iButton 在易受影响人群中的实用性，包括神经退行性疾病和记忆障碍患者以及儿科人群。
