Tabatabaei M H, Arami S, Zandi S, Bassir S H
Restorative Department, Dentistry Faculty, Dental Research Center, Tehran University of Medical SciencesTehran, Iran.
Minerva Stomatol. 2011 Apr;60(4):159-65.
Postcuring elution of unreacted monomers has harmful effects on mechanical characteristics and biocompatibility of resin composite restorations. The purpose of this study was to evaluate the amount of eluted Bis-GMA and TEGDMA monomers from a hybrid dental composite cured with LED or halogen curing unit after immersing in saliva or water.
Thirty-six composite disc specimens (Hybrid Filtek Z250,3M-ESPE, USA) were made and divided in four groups. After polymerization with LED or halogen curing units, samples were immersed in water or saliva for 24 hours. The amounts of each monomer (Bis-GMA and TEGDMA) released in different mediums were detected by high-performance liquid chromatography (HPLC). Data were analyzed with two-way ANOVA and one-way ANOVA tests.
The samples were immersed in water, in both curing methods, released significantly more Bis-GMA than TEGDMA (P<0.05). The total monomers eluted was higher in samples cured with halogen curing unit than LED (P=0.001); in addition, saliva caused elution of more monomer than water (P=0.007).
In conclusion, chemical property of monomers, power of curing light unit and the type of immersion media play key roles in the quantity of eluted monomers from composite resins. Saliva and halogen curing unit can cause greater monomer leaching from hybrid resins composite.
未反应单体的后固化洗脱对树脂复合材料修复体的机械性能和生物相容性具有有害影响。本研究的目的是评估用发光二极管（LED）或卤素固化灯固化的牙科复合树脂在唾液或水中浸泡后，双甲基丙烯酸缩水甘油酯（Bis-GMA）和双甲基丙烯酸三乙二醇酯（TEGDMA）单体的洗脱量。
制作36个复合树脂圆盘试件（美国3M-ESPE公司的Filtek Z250混合型复合树脂），并分为四组。用LED或卤素固化灯聚合后，将样本在水或唾液中浸泡24小时。通过高效液相色谱法（HPLC）检测在不同介质中释放的每种单体（Bis-GMA和TEGDMA）的量。数据采用双向方差分析和单向方差分析进行分析。
在两种固化方法中，浸泡在水中的样本释放的Bis-GMA明显多于TEGDMA（P<0.05）。用卤素固化灯固化的样本洗脱的总单体量高于用LED固化的样本（P=0.001）；此外，唾液导致的单体洗脱量多于水（P=0.007）。
总之，单体的化学性质、固化灯的功率和浸泡介质的类型对复合树脂中洗脱单体的量起着关键作用。唾液和卤素固化灯会导致混合型复合树脂中更多的单体浸出。
