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过敏性紫癜与复发性心内膜炎的罕见关联。

Rare association of Henoch-Schönlein Purpura with recurrent endocarditis.

作者信息

Berquist Jilaine Bolek, Bartels Christie Michels

机构信息

University of Wisconsin-School of Medicine and Public Health, Department of Internal Medicine, Rheumatology, Madison, Wis USA.

出版信息

WMJ. 2011 Feb;110(1):38-40.

PMID:21473512
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3074230/
Abstract

We report a rare association of Henoch-Schönlein Purpura with recurrent endocarditis in a 36-year-old man presenting with rash and renal failure. Bacterial endocarditis can be complicated by renal failure of various etiologies. Biopsy may distinguish these and guide therapy as seen in this case. Here, timely diagnosis of Henoch-Schönlein Purpura in the setting of recurrent methacillin sensitive staphylococcus endocarditis led to steroid therapy and renal recovery. This is a rare reported case of Henoch-Schönlein Purpura during an episode of recurrent adult endocarditis that also highlights the complex interplay between genetic susceptibility and immune responses.

摘要

我们报告了一例罕见的病例,一名36岁出现皮疹和肾衰竭的男性,患过敏性紫癜合并复发性心内膜炎。细菌性心内膜炎可并发各种病因的肾衰竭。活检可对这些情况进行鉴别并指导治疗,本病例即是如此。在此病例中,在复发性甲氧西林敏感金黄色葡萄球菌心内膜炎背景下及时诊断出过敏性紫癜,从而进行了类固醇治疗并使肾功能恢复。这是一例罕见的复发性成人感染性心内膜炎期间发生过敏性紫癜的报告病例,该病例还凸显了遗传易感性与免疫反应之间复杂的相互作用。

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本文引用的文献

1
Cytoplasmic antineutrophil cytoplasmic antibody positive pauci-immune glomerulonephritis associated with infectious endocarditis.与感染性心内膜炎相关的细胞质抗中性粒细胞胞质抗体阳性寡免疫性肾小球肾炎。
Clin Nephrol. 2006 Dec;66(6):447-54. doi: 10.5414/cnp66447.
2
Henoch-Schonlein purpura secondary to subacute bacterial endocarditis.亚急性细菌性心内膜炎继发的亨诺赫-舍恩莱因紫癜
Cutis. 2002 Apr;69(4):269-73.
3
Henoch-Schönlein Purpura in adults: outcome and prognostic factors.成人过敏性紫癜:结局与预后因素
J Am Soc Nephrol. 2002 May;13(5):1271-8. doi: 10.1097/01.asn.0000013883.99976.22.
4
Specific T-cell receptor usage with cytokinemia in Henoch-Schönlein purpura nephritis associated with Staphylococcus aureus infection.与金黄色葡萄球菌感染相关的过敏性紫癜性肾炎中特定T细胞受体的使用与细胞因子血症
J Intern Med. 2001 Apr;249(4):289-95. doi: 10.1046/j.1365-2796.2001.00815.x.
5
Renal pathological findings in infective endocarditis.感染性心内膜炎的肾脏病理表现
Nephrol Dial Transplant. 2000 Nov;15(11):1782-7. doi: 10.1093/ndt/15.11.1782.
6
Predictors of prognosis and risk of acute renal failure in bacterial endocarditis.细菌性心内膜炎的预后预测因素及急性肾衰竭风险
Clin Nephrol. 1998 Feb;49(2):96-101.
7
Henoch-Schönlein purpura in adulthood and childhood: two different expressions of the same syndrome.成人和儿童的过敏性紫癜:同一综合征的两种不同表现形式。
Arthritis Rheum. 1997 May;40(5):859-64. doi: 10.1002/art.1780400513.
8
Henoch-Schönlein purpura complicating staphylococcal endocarditis in a heroin addict.一名海洛因成瘾者患过敏性紫癜并发葡萄球菌性心内膜炎。
Am J Nephrol. 1987;7(2):137-9. doi: 10.1159/000167450.