过敏性紫癜与复发性心内膜炎的罕见关联。
Rare association of Henoch-Schönlein Purpura with recurrent endocarditis.
作者信息
Berquist Jilaine Bolek, Bartels Christie Michels
机构信息
University of Wisconsin-School of Medicine and Public Health, Department of Internal Medicine, Rheumatology, Madison, Wis USA.
出版信息
WMJ. 2011 Feb;110(1):38-40.
Abstract
We report a rare association of Henoch-Schönlein Purpura with recurrent endocarditis in a 36-year-old man presenting with rash and renal failure. Bacterial endocarditis can be complicated by renal failure of various etiologies. Biopsy may distinguish these and guide therapy as seen in this case. Here, timely diagnosis of Henoch-Schönlein Purpura in the setting of recurrent methacillin sensitive staphylococcus endocarditis led to steroid therapy and renal recovery. This is a rare reported case of Henoch-Schönlein Purpura during an episode of recurrent adult endocarditis that also highlights the complex interplay between genetic susceptibility and immune responses.
摘要
我们报告了一例罕见的病例，一名36岁出现皮疹和肾衰竭的男性，患过敏性紫癜合并复发性心内膜炎。细菌性心内膜炎可并发各种病因的肾衰竭。活检可对这些情况进行鉴别并指导治疗，本病例即是如此。在此病例中，在复发性甲氧西林敏感金黄色葡萄球菌心内膜炎背景下及时诊断出过敏性紫癜，从而进行了类固醇治疗并使肾功能恢复。这是一例罕见的复发性成人感染性心内膜炎期间发生过敏性紫癜的报告病例，该病例还凸显了遗传易感性与免疫反应之间复杂的相互作用。
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