Centre for Contact Lens Research, School of Optometry, University of Waterloo, Waterloo, Ontario, Canada.
Invest Ophthalmol Vis Sci. 2011 Jul 29;52(8):5812-7. doi: 10.1167/iovs.10-7006.
To determine the between-scale agreement of grading estimates obtained with cross-calibrated McMonnies/Chapman-Davies (MC-D), Institute for Eye Research (IER), Efron, and Validated Bulbar Redness (VBR) grading scales.
Modified reference images of each grading scale were positioned on a desk according to their perceived redness (within a 0 to 100 range) as determined in a previous psychophysical scaling experiment. Ten observers were asked to represent perceived bulbar redness of 16 sample images by placing them, one at a time, relative to the reference images of each scale. Only 0 and 100 were marked on the scale, but not the numerical position of the reference images. Perceived redness was taken as the measured position of the placed image from 0 and was averaged across observers.
Overall, perceived redness depended on the sample image and the reference scale used (repeated measures ANOVA; P = 0.0008); six sample images had a perceived redness that was significantly different between at least two of the scales. Between-scale correlation coefficients of concordance ranged from 0.93 (IER vs. Efron) to 0.98 (VBR vs. Efron). Between-scale coefficients of repeatability ranged from five units (IER vs. VBR) to eight units (IER vs. Efron) of the 0 to 100 range.
The use of cross-calibrated reference grades for bulbar redness grading scales allows comparison of grading estimates obtained with different scales. Perceived redness is dependent on the dynamic range of the reference images of the scale, with redness estimates generally being found to be higher for scales with a shorter dynamic range.
确定经交叉校准的 McMonnies/Chapman-Davies（MC-D）、眼研究所（IER）、Efron 和经验证的球结膜红斑（VBR）分级量表的分级估计值之间的跨尺度一致性。
根据先前的心理物理标度实验中确定的感知红斑程度（0 到 100 范围内），将每个分级量表的修改参考图像放置在桌子上。要求 10 名观察者通过将每个量表的参考图像一次一个地放置在参考图像上来表示 16 个样本图像的感知球结膜红斑。仅在量表上标记 0 和 100，而不标记参考图像的数字位置。感知红斑被视为从 0 放置的图像的测量位置，并在观察者之间平均。
总体而言，感知红斑取决于样本图像和使用的参考量表（重复测量方差分析；P = 0.0008）；六个样本图像的感知红斑在至少两个量表之间存在显著差异。一致性的跨尺度相关系数范围从 0.93（IER 与 Efron）到 0.98（VBR 与 Efron）。跨尺度可重复性系数范围从 0 到 100 范围内的 5 个单位（IER 与 VBR）到 8 个单位（IER 与 Efron）。
使用交叉校准的参考等级进行球结膜红斑分级允许比较使用不同量表获得的分级估计值。感知红斑取决于量表参考图像的动态范围，具有较短动态范围的量表的红斑估计值通常较高。
