University of Hohenheim, Stuttgart, Germany.
Theor Appl Genet. 2011 Jul;123(2):283-92. doi: 10.1007/s00122-011-1583-y. Epub 2011 Apr 8.
There is increasing awareness that epistasis plays a role for the determination of complex traits. This study employed an association mapping approach in a large panel of 455 diverse European elite soft winter wheat lines. The genotypes were evaluated in multi-environment trials and fingerprinted with SSR markers to dissect the underlying genetic architecture of grain yield and heading time. A linear mixed model was applied to assess marker-trait associations incorporating information of covariance among relatives. Our findings indicate that main effects dominate the control of grain yield in wheat. In contrast, the genetic architecture underlying heading time is controlled by main and epistatic effects. Consequently, for heading time it is important to consider epistatic effects towards an increased selection gain in marker-assisted breeding.
人们越来越意识到，上位性在复杂性状的决定中起着作用。本研究采用关联作图方法，对 455 个来自不同欧洲的优质软冬小麦品系进行了研究。这些基因型在多环境试验中进行了评估，并使用 SSR 标记进行了指纹分析，以剖析粒重和抽穗期的潜在遗传结构。应用线性混合模型来评估包含亲属间协方差信息的标记-性状关联。我们的研究结果表明，主效在小麦粒重的控制中占主导地位。相比之下，抽穗期的遗传结构受主效和上位性效应的控制。因此，对于抽穗期来说，考虑上位性效应对提高标记辅助选择的增益是很重要的。
