猴病毒40中DNA复制起点边界的定义。
Definition of the boundaries of the origin of DNA replication in simian virus 40.
作者信息
Subramanian K N, Shenk T
出版信息
Nucleic Acids Res. 1978 Oct;5(10):3635-42. doi: 10.1093/nar/5.10.3635.
Abstract
We have determined by use of DNA sequencing techniques the exact location of the deletion in d1 892, a viable deletion mutant of Simian virus 40 (SV40) reported to map very near the unique replication origin or SV40. With the help of this localization we have narrowed down the boundaries of the replication origin to 85 nucleotides within the sequence of SV40.
摘要
我们利用DNA测序技术确定了d1 892中缺失的精确位置，d1 892是猿猴病毒40（SV40）的一个存活缺失突变体，据报道其定位非常靠近SV40的独特复制起点。借助这一定位，我们已将复制起点的边界缩小至SV40序列内的85个核苷酸。
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