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德国、意大利和西班牙胃食管反流病和 Barrett 综合征的流行病学和社会成本。

Epidemiology and societal costs of gastroesophageal reflux disease and Barrett's syndrome in Germany, Italy and Spain.

机构信息

Universitat de Barcelona, Diagonal 690, 08034, Barcelona, Spain.

出版信息

Expert Rev Pharmacoecon Outcomes Res. 2011 Apr;11(2):225-32. doi: 10.1586/erp.11.5.

DOI:10.1586/erp.11.5
PMID:21476824
Abstract

AIM

To estimate the economic consequences for society arising from populations with poorly treated gastroesophageal reflux disease (GERD) and Barrett's esophagus in Germany, Italy and Spain.

METHODS

The following epidemiologic data were used: total population figures, the prevalence and incidence of GERD and its complications, and data on patients with poorly treated GERD, as well as data on treatment costs and active workers' presenteeism and absenteeism. These data were used to calculate the economic consequences arising from the population with poorly treated GERD and Barrett's esophagus for the healthcare system and employers in each country.

RESULTS

The size of the population with poorly treated GERD with Barrett's esophagus was estimated to be 29,678 in Spain, 19,327 in Germany and 10,079 in Italy. Costs for the healthcare systems in Spain, Germany and Italy for the population with poorly treated GERD with Barrett's esophagus were estimated to be €18, 12 and 7 million, respectively, for each country. Total costs for absenteeism and presenteeism for employers due to poorly treated GERD with Barrett's esophagus were €10 million for Germany, €1 million for Italy and none for Spain.

CONCLUSION

Costs due to poorly treated GERD with Barrett's esophagus represent a substantial burden for the healthcare systems of all three studied countries. Costs for employers owing to absenteeism or presenteeism of employees were low or no costs were found.

摘要

目的

评估德国、意大利和西班牙人群中治疗不佳的胃食管反流病(GERD)和巴雷特食管对社会造成的经济后果。

方法

使用了以下流行病学数据:总人口数、GERD 及其并发症的患病率和发病率,以及治疗不佳的 GERD 患者数据,以及治疗成本和在职员工的生产力损失和缺勤数据。这些数据用于计算每个国家医疗保健系统和雇主因治疗不佳的 GERD 和巴雷特食管患者而产生的经济后果。

结果

估计西班牙、德国和意大利治疗不佳的 GERD 伴巴雷特食管患者的人口规模分别为 29678 人、19327 人和 10079 人。估计西班牙、德国和意大利治疗不佳的 GERD 伴巴雷特食管患者的医疗保健系统成本分别为 1800 万欧元、1200 万欧元和 700 万欧元。由于治疗不佳的 GERD 伴巴雷特食管,德国雇主的缺勤和生产力损失总成本为 1000 万欧元,意大利为 100 万欧元,西班牙则没有。

结论

治疗不佳的 GERD 伴巴雷特食管的成本给所有三个研究国家的医疗保健系统带来了重大负担。由于员工缺勤或生产力损失导致的雇主成本较低或没有。

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