弥散磁共振成像在急性缺血性脑卒中的临床应用。

Clinical applications of diffusion MR imaging for acute ischemic stroke.

机构信息

Division of Diagnostic and Interventional Neuroradiology, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, Gray 241, Boston, MA 02114, USA.

出版信息

Neuroimaging Clin N Am. 2011 Feb;21(1):51-69, vii. doi: 10.1016/j.nic.2011.02.002.

DOI:10.1016/j.nic.2011.02.002

PMID:21477751

Abstract

Diffusion magnetic resonance imaging is the best imaging tool for detecting acute ischemic brain injury. Studies have shown its high accuracy for delineating irreversible tissue damage within the first few hours after stroke onset; however, the true value of any diagnostic tool is whether it can be used to guide clinical management. This review discusses the role of diffusion imaging in the evaluation of the patient with acute ischemic stroke, and how this role is influenced by other important stroke-related variables, including the level of vessel occlusion and the clinical deficit. The review focuses on decision-making for intravenous and intra-arterial reperfusion therapies.

摘要

弥散磁共振成像是检测急性缺血性脑损伤的最佳成像工具。研究表明，它在脑卒中发作后数小时内准确勾画不可逆转的组织损伤方面具有很高的准确性；然而，任何诊断工具的真正价值在于其是否可用于指导临床管理。本文综述了弥散成像在急性缺血性脑卒中患者评估中的作用，以及其他重要的与脑卒中相关的变量（包括血管闭塞程度和临床缺损程度）如何影响其作用。本文重点讨论了静脉和动脉内再灌注治疗的决策。