Viscoli C, Castagnola E, Moroni C, Garaventa A, Manno G, Savioli C
Department of Infectious Diseases, University of Genoa, Italy.
Eur J Clin Microbiol Infect Dis. 1990 Oct;9(10):773-6. doi: 10.1007/BF02184694.
Two cases of Fusarium infection in children with neuroblastoma are reported. One of the patients had an overwhelming infection and the diagnosis was based on isolation of Fusarium moniliforme from blood and skin biopsy, and histological findings. The second patient developed chronic polyarthritis and Fusarium solani was cultured from synovial fluid samples taken from two different joints four months apart. No histological documentation of infection was obtained. The response to antifungal therapy was unfavourable. Both patients died, but in the second case the relationship between fungal infection and death was not established.
报告了两例神经母细胞瘤患儿的镰刀菌感染病例。其中一名患者发生了严重感染，诊断依据是从血液和皮肤活检中分离出串珠镰刀菌以及组织学检查结果。第二名患者出现慢性多关节炎，相隔四个月从两个不同关节采集的滑液样本中培养出茄病镰刀菌。未获得感染的组织学证据。抗真菌治疗反应不佳。两名患者均死亡，但在第二例中，真菌感染与死亡之间的关系未明确。
