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串珠镰刀菌作为一名免疫抑制患者播散性感染的病原体

Fusarium proliferatum as an agent of disseminated infection in an immunosuppressed patient.

作者信息

Summerbell R C, Richardson S E, Kane J

机构信息

Mycology Laboratory, Ontario Ministry of Health, Toronto, Ontario, Canada.

出版信息

J Clin Microbiol. 1988 Jan;26(1):82-7. doi: 10.1128/jcm.26.1.82-87.1988.

DOI:10.1128/jcm.26.1.82-87.1988
PMID:3422646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC266194/
Abstract

Fusarium proliferatum was reported as the agent of a fatal disseminated infection in a child with lymphoblastic leukemia. The fungus has not been reported previously to cause disease in humans, but it is closely related to the known opportunistic pathogen F. verticillioides. It was distinguished by the production of clavate microconidia in chains from proliferating phialides. Resistance to amphotericin B and flucytosine in vitro was shown.

摘要

层出镰刀菌被报道为一名淋巴细胞白血病患儿致命播散性感染的病原体。此前该真菌尚未有在人类中致病的报道，但它与已知的机会致病菌拟轮枝镰孢密切相关。其特征是从增殖的瓶梗产生链状的棒状小分生孢子。该菌在体外表现出对两性霉素B和氟胞嘧啶耐药。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afb8/266194/4a7c2c274774/jcm00073-0111-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afb8/266194/6e180aab9409/jcm00073-0109-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afb8/266194/bc8f99f0b6cc/jcm00073-0110-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afb8/266194/4a7c2c274774/jcm00073-0111-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afb8/266194/6e180aab9409/jcm00073-0109-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afb8/266194/bc8f99f0b6cc/jcm00073-0110-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afb8/266194/4a7c2c274774/jcm00073-0111-a.jpg

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本文引用的文献

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A comparative study of the toxicity of Fusarium verticillioides (= F. moniliforme) to horses, primates, pigs, sheep and rats.串珠镰刀菌（= 禾谷镰刀菌）对马、灵长类动物、猪、绵羊和大鼠毒性的比较研究。
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Urinary Tract Infection (UTI) Caused by Fusarium proliferatum in an Agranulocytosis Patient and a Review of Published Reports.1例粒细胞缺乏症患者由层出镰刀菌引起的尿路感染及已发表报告的综述
Mycopathologia. 2016 Feb;181(1-2):131-5. doi: 10.1007/s11046-015-9937-7. Epub 2015 Sep 7.
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Dermatitis in the Fringe-Toed Lizard, Acanthodactylus nilsoni Rastegar-Pouyani, 1998 (Sauria: Lacertidae) Associated with Fusarium proliferatum.尼尔森沙趾虎（Acanthodactylus nilsoni Rastegar-Pouyani，1998年）（有鳞目：蜥蜴科）的皮炎与层出镰刀菌有关。
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[Disseminated infections caused by Fusarium sp].
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Invasive Fusarium infections in bone marrow transplant recipients.骨髓移植受者的侵袭性镰刀菌感染
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