Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Am J Obstet Gynecol. 2011 Jul;205(1):73.e1-6. doi: 10.1016/j.ajog.2011.02.054. Epub 2011 Feb 23.
We investigated the relation between total fluid intake and incident urinary incontinence in the Nurses' Health Study cohorts.
We measured daily fluid intake using food frequency questionnaires among 65,167 women, who were 37-79 years old, without urinary incontinence at study baseline (2000-2001). Women reported incontinence incidence on questionnaires during 4 years of follow-up evaluation. Multivariable-adjusted hazard ratios and 95% confidence intervals were calculated with Cox proportional hazards models.
We found no association between total fluid intake and risk of incident incontinence (hazard ratio, 1.04; 95% confidence interval, 0.98-1.10; comparing top vs bottom quintile of fluid intake). In analyses of incontinence type, total fluid intake was not associated with risks of incident stress, urgency, or mixed incontinence.
No significant risk of incident urinary incontinence was found with higher fluid intake in women. These findings suggest that women should not restrict their fluid intake to prevent incontinence development.
我们调查了总液体摄入量与护士健康研究队列中发生尿失禁之间的关系。
我们使用食物频率问卷在 65167 名年龄在 37-79 岁、基线时无尿失禁的女性中测量了每日液体摄入量。在 4 年的随访评估中，女性通过问卷报告了失禁的发生情况。使用 Cox 比例风险模型计算多变量调整后的风险比和 95%置信区间。
我们没有发现总液体摄入量与失禁风险之间存在关联（风险比，1.04；95%置信区间，0.98-1.10；比较摄入量最高和最低五分位数）。在分析失禁类型时，总液体摄入量与新发压力性、急迫性或混合性失禁的风险无关。
女性摄入更多液体并不会显著增加发生尿失禁的风险。这些发现表明，女性不应为了预防失禁的发生而限制液体摄入。
