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克林霉素意外动脉内注射致血管损伤:药物不良反应报告。

Vascular injury following accidental intra-arterial injection of clindamycin: adverse drug reaction report.

机构信息

Department of Anesthesiology, Rambam Health Care Campus, Haifa, Israel.

出版信息

Minerva Anestesiol. 2011 Apr;77(4):468-9. Epub 2011 Mar 1.

PMID:21483392
Abstract

Clindamycin in a commonly used antibiotic, considered safe for oral, intravenous and intra-arterial use. We present a case of a patient that received an inadvertent injection clindamycin 600 mg in 4 mL through a radial arterial line. The patient presented signs and symptoms of vascular occlusion and despite aggressive pharmacological and medical treatment developed massive and severe tissue injury.

摘要

克林霉素是一种常用的抗生素,被认为可安全用于口服、静脉和动脉内给药。我们报告了 1 例患者,该患者通过桡动脉通路意外注射了 600mg 克林霉素(4ml)。该患者出现血管闭塞的体征和症状,尽管进行了积极的药物和医疗治疗,但仍发生了大面积和严重的组织损伤。

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