生物信息学在理论生物学中的起源。
The roots of bioinformatics in theoretical biology.
机构信息
Theoretical Biology and Bioinformatics Group, Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
出版信息
PLoS Comput Biol. 2011 Mar;7(3):e1002021. doi: 10.1371/journal.pcbi.1002021. Epub 2011 Mar 31.
Abstract
From the late 1980s onward, the term "bioinformatics" mostly has been used to refer to computational methods for comparative analysis of genome data. However, the term was originally more widely defined as the study of informatic processes in biotic systems. In this essay, I will trace this early history (from a personal point of view) and I will argue that the original meaning of the term is re-emerging.
摘要
从上世纪 80 年代末开始，“生物信息学”一词主要用于指代基因组数据分析的计算方法。然而，该术语的原始定义更为广泛，指的是生物系统中信息处理的研究。在本文中，我将追溯这一早期历史（从个人观点出发），并认为该术语的原始含义正在重现。
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