Wu Rui, Xie Jian-xiang, Zhao Feng-da
The First Affiliated Hospital of Nanchang University, Jiangxi.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011 Mar;31(3):319-22.
To make out a computerized formula to diagnose eye's signs of blood-stasis syndrome (BSS), and to improve the previous diagnostic methods by naked eyes.
The formula was created by detecting and analyzing the changes of eye's signs in 544 patients (261 of non-BSS and 283 of BSS) quantitatively, adopting computer's color scale principle. And the sensitivity, specificity and accuracy of the formula were verified in 382 patients (97 non-BSS and 285 of BSS). The computerized integral was compared with the naked eye integral, and the normal reference value was calculated with percentile.
Various observatory indices of eye's sign were positively correlated with BSS. The specificity of the computerized method was 83.5%, and the diagnostic sensitivity was 89.8%, the accuracy 88.2%, and the correct index 0.733. Comparisons between the computerized integral method and the naked eye integral method showed significant difference in patients of non-BSS or of BSS in various degrees (including mild, moderate and severe) (P < 0.01). The reference value of the naked eye method was below 15.
The computerized formula of eye's signs has higher specificity and sensitivity in the diagnosis of BSS, while the naked eye integral method is proved to be useful.
制定一种用于诊断眼部血瘀证体征的计算机化公式，以改进以往的肉眼诊断方法。
采用计算机颜色标尺原理，对544例患者（非血瘀证261例，血瘀证283例）的眼部体征变化进行定量检测和分析，建立公式。并在382例患者（非血瘀证97例，血瘀证285例）中验证该公式的敏感性、特异性和准确性。将计算机积分与肉眼积分进行比较，并用百分位数计算正常参考值。
眼部体征的各项观察指标与血瘀证呈正相关。计算机化方法的特异性为83.5%，诊断敏感性为89.8%，准确性为88.2%，正确指数为0.733。计算机积分法与肉眼积分法在不同程度（包括轻度、中度和重度）的非血瘀证或血瘀证患者中比较，差异有统计学意义（P<0.01）。肉眼法的参考值低于15。
眼部体征计算机化公式在血瘀证诊断中具有较高的特异性和敏感性，同时证明肉眼积分法也有实用价值。
