运动员心脏与衰竭心脏：信号转导能否解释两种截然不同的结局？
The athlete's heart vs. the failing heart: can signaling explain the two distinct outcomes?
机构信息
Cardiac Hypertrophy Laboratory, Baker IDI Heart and Diabetes Institute, University of Melbourne, Melbourne, Australia.
出版信息
Physiology (Bethesda). 2011 Apr;26(2):97-105. doi: 10.1152/physiol.00043.2010.
PMID:21487028
Abstract
Cardiac remodeling is typically associated with disease and can lead to heart failure. In contrast, remodeling that occurs in the athlete's heart is considered an adaptive physiological response. This review provides an overview of signaling mechanisms responsible for inducing left ventricular hypertrophy in the athlete's heart and in settings of pathological hypertrophy and heart failure.
摘要
心脏重构通常与疾病有关，并可导致心力衰竭。相比之下，运动员心脏中的重构被认为是一种适应性的生理反应。这篇综述概述了导致运动员心脏和病理性心肌肥厚及心力衰竭中心室重构的信号机制。
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