对于有认知问题的患者，应考虑进行脑脊液分析。
Cerebrospinal fluid analysis should be considered in patients with cognitive problems.
作者信息
Zetterberg Henrik, Mattsson Niklas, Blennow Kaj
机构信息
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, 431 80 Mölndal, Sweden.
出版信息
Int J Alzheimers Dis. 2010 Jul 14;2010:163065. doi: 10.4061/2010/163065.
Abstract
Hepatologists assay liver enzymes and cardiologists structural heart proteins in serum to diagnose and monitor their patients. This way of thinking has not quite made it into the memory clinics yet, in spite of the availability of validated cerebrospinal fluid biomarkers for key pathological events in the brain in neurodegeneration. Here, we argue that a spinal tap should be considered in all patients who seek medical advice for memory problems and list the highly relevant clinical questions CSF analyses can address.
摘要
肝病学家检测血清中的肝酶，心脏病学家检测血清中的心脏结构蛋白，以诊断和监测他们的患者。尽管有经过验证的脑脊液生物标志物可用于检测神经退行性疾病中大脑关键病理事件，但这种思维方式尚未完全进入记忆诊所。在此，我们认为，所有因记忆问题寻求医疗建议的患者都应考虑进行腰椎穿刺，并列出脑脊液分析可以解决的高度相关的临床问题。
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