Yamaguchi N, Tong L J, Yamamura Y, Otsuka G, Tamura Y, Kita M, Imanishi J
Département de Microbiologie, Université Médicale de la Préfecture de Kyoto, Japan.
C R Seances Soc Biol Fil. 1990;184(2):187-92.
The effects of human interferons (HuIFN) on the human osteosarcoma cells were examined. HuIFN-alpha, -beta and -gamma enhanced dose-dependently the cell growth. There was no difference in the degree of the enhancement of the cell growth among HuIFN-alpha, -beta and -gamma. The higher the cell density was, the lower the degree of the enhancement of the cell growth. When HuIFN-gamma was neutralized with anti-HuIFN-gamma, the enhancement of cell growth was not found.