School of Science, 'Xi'an Jiaotong University, Shann Xi 710049, People's Republic of China.
Biomaterials. 2011 Jul;32(21):4877-84. doi: 10.1016/j.biomaterials.2011.03.029. Epub 2011 Apr 13.
Surface-enhanced Raman scattering-based signal detection and molecular identification faces the lack of reproducibility and reliability thus hampers its practical applications. Here, we demonstrate a facile particle mediated aggregation protocol to synthesize highly roughened mesosuperstructure--silver polyhedral mesocages. The individual silver octahedral mesocage, owing to highly-roughed surface topography, anisotropic growth as well as intraparticle effect, creates homogenously distributed multiple effective hot spots on the surface of single mesoparticle, hereby exhibits a high reproducibility and an unusual SERS enhancement, i.e., ∼ 10(8)-10(9) magnitude. As such, the current protocol opens avenues for the fabrication of structurally reproducible mesosuperstructure-based SERS sensors.
基于表面增强拉曼散射的信号检测和分子识别面临着重现性和可靠性的缺乏，从而阻碍了其实际应用。在这里，我们展示了一种简单的颗粒介导聚集方案，用于合成高度粗糙的介观超结构-银多面体介孔笼。由于具有高度粗糙的表面形貌、各向异性生长和颗粒内效应，单个银八面体介孔笼在单个介孔粒子的表面上创造了均匀分布的多个有效热点，从而表现出高重现性和异常的 SERS 增强，即 ∼ 10(8)-10(9)数量级。因此，该方案为制备结构重现性的基于介观超结构的 SERS 传感器开辟了道路。
