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术中冷生理盐水浸泡纱布压迫与皮质类固醇联合应用对鼻整形术发病率的影响。

Efficacy of the combination of intraoperative cold saline-soaked gauze compression and corticosteroids on rhinoplasty morbidity.

机构信息

Istanbul Education and Research Hospital, Department of Otorhinolaryngology, Istanbul, Turkey.

出版信息

Otolaryngol Head Neck Surg. 2011 May;144(5):698-702. doi: 10.1177/0194599811400377.

DOI:10.1177/0194599811400377
PMID:21493314
Abstract

OBJECTIVE

The basic aim of this study was to minimize intraoperative bleeding, postoperative eyelid edema, and periorbital ecchymosis and to reduce morbidity with a combination of cold saline-soaked gauze compression and intraoperative single-dose corticosteroids.

STUDY DESIGN

The study was designed as a prospective, double-blind, randomized controlled study. Three hundred patients who underwent septorhinoplasty were included.

SETTING

A tertiary referral hospital in Turkey.

SUBJECTS AND METHODS

Three hundred patients undergoing septorhinoplasty were divided into 2 groups. A single dose of 10 mg dexamethasone was intravenously administered in all cases at the beginning of the operation. In the study group, the nasal dorsum was continuously compressed with cold saline-soaked gauze during the operation. In the control group, the nasal dorsum was compressed with dry gauze continuously during surgery. The operation time and amount of bleeding were recorded during surgery. Degree of eyelid edema and periorbital soft tissue ecchymosis was recorded at 24 hours and on postoperative days 2, 3, 5, and 7 by 2 investigators.

RESULTS

The operation time was significantly shorter in the study group than in the control group. Eyelid edema and periorbital ecchymosis were significantly decreased in the study group at the following postoperative days 1, 3, 5, and 7 (P < .05).

CONCLUSION

Bleeding, edema, and ecchymosis are the main morbidities of rhinoplasty. It is highly probable that cold compression and intraoperative corticosteroids have synergistic effects on these morbidities, especially by the intraoperative control of bleeding.

摘要

目的

本研究的基本目的是通过组合使用冷盐水浸泡纱布压迫和术中单次剂量皮质类固醇来最大限度地减少术中出血、术后眼睑水肿和眶周瘀斑,并降低发病率。

研究设计

本研究设计为前瞻性、双盲、随机对照研究。纳入了 300 例接受鼻中隔成形术的患者。

研究地点

土耳其的一家三级转诊医院。

受试者和方法

将 300 例接受鼻中隔成形术的患者分为 2 组。所有患者在手术开始时均静脉注射 10mg 地塞米松。在研究组中,在手术过程中持续用冷盐水浸泡的纱布对鼻背进行连续压迫。在对照组中,在手术过程中持续用干纱布对鼻背进行连续压迫。记录手术过程中的手术时间和出血量。由 2 名研究者在术后 24 小时和第 2、3、5 和 7 天记录眼睑水肿和眶周软组织瘀斑的程度。

结果

研究组的手术时间明显短于对照组。研究组在术后第 1、3、5 和 7 天的眼睑水肿和眶周瘀斑明显减少(P<0.05)。

结论

出血、水肿和瘀斑是鼻整形术的主要并发症。冷压迫和术中皮质类固醇对这些并发症很可能具有协同作用,尤其是通过术中控制出血。

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