University of Wisconsin-Madison School of Medicine and Public Health, Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, Madison, WI 53706, USA.
Otolaryngol Head Neck Surg. 2011 Jan;144(1):108-13. doi: 10.1177/0194599810390893.
Evaluate the effect of vocal fold surface dehydration on mucosal wave amplitude and frequency.
Controlled test-retest.
Larynges were mounted on an excised larynx phonation system and attached to a pseudolung in a triple-walled sound-attenuated room that eliminated background noise and maintained a stabilized room temperature and humidity level.
High-speed video was recorded for 8 excised canine larynges during exposure to dehumidified air at 20 cm H(2)O. Control trials consisted of high-speed videos recorded for 2 excised canine larynges during exposure to humidified air at the same pressure.
In the majority of larynges, increased levels of dehydration were correlated with decreased amplitude and frequency. The slope of the linear regression fitted to the change in amplitude (P = .003) and the percent change (P < .001) between the initial and final trials were significantly decreased in dehydrated larynges. These measurements with respect to the change in frequency were also significantly decreased in dehydrated larynges (P < .001; P = .027).
Vocal fold surface dehydration caused a decrease in mucosal wave amplitude and frequency. This study provides objective, quantitative support for the mechanism of voice deterioration observed after extreme surface dehydration.
评估声带表面脱水对黏膜波幅度和频率的影响。
对照测试-再测试。
喉标本安装在离体喉发声系统上，并连接到三重隔音室中的假性肺，以消除背景噪声，并维持稳定的室温与湿度水平。
在 20cmH₂O 的除湿空气中，对 8 个离体犬喉进行高速录像。对照试验包括在相同压力下，对 2 个离体犬喉进行高速录像，暴露于加湿空气中。
在大多数喉中，脱水程度增加与幅度和频率降低相关。在脱水喉中，拟合幅度变化的线性回归的斜率（P=0.003）和初始与最终试验之间的幅度百分比变化（P<0.001）显著降低。脱水喉中，频率变化的这些测量值也显著降低（P<0.001；P=0.027）。
声带表面脱水导致黏膜波幅度和频率降低。本研究为观察到的极度表面脱水后声音恶化的机制提供了客观、定量的支持。
