美国关于 HIV 口腔暴露前预防的政策视角。
A US policy perspective on oral preexposure prophylaxis for HIV.
机构信息
Department of Public Policy, University of California, Los Angeles School of Public Affairs, Los Angeles, CA 90095-1656, USA.
出版信息
Am J Public Health. 2011 Jun;101(6):982-5. doi: 10.2105/AJPH.2010.300066. Epub 2011 Apr 14.
Abstract
Orally administered preexposure prophylaxis is an innovative and controversial HIV prevention strategy involving the regular use of antiretroviral medications by uninfected individuals. Antiretroviral medications protect against potential HIV infection by reducing susceptibility to the virus. Recent clinical trial results indicate that preexposure prophylaxis can be safe and efficacious for men who have sexual intercourse with men, yet there remain policy considerations surrounding costs, opportunity costs, and ethical issues that must be addressed before broad implementation in the United States.
摘要
口服暴露前预防是一种创新且有争议的 HIV 预防策略，涉及未感染个体定期使用抗逆转录病毒药物。抗逆转录病毒药物通过降低对病毒的易感性来预防潜在的 HIV 感染。最近的临床试验结果表明，暴露前预防对与男性发生性行为的男性是安全有效的，但在广泛实施之前，仍存在与成本、机会成本和伦理问题相关的政策考虑因素。
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