K. GIRISH, M.D., Department of Psychiatry, National Institute of Mental Health and Neuro Sciences, Bangalore -560 029.
Indian J Psychiatry. 1998 Oct;40(4):327-30.
Research on determinants of ECT seizure threshold is inadequate. In view of differences in ECT populations and confounding factors, there is a need for examining this in our population. Consecutive consenting inpatients (N=100), referred for bilateral (BL) ECT by treating psychiatrists at National Institute of Mental Health and Neuro Sciences Hospital, Bangalore, formed the sample for the study. Thiopentone, succinylcholine and atropine were used for modification. Seizure threshold (dependent variable) was determined by titration method at the first ECT. The independent variables were age, gender, diagnosis, illness severity (Clinical Global Impression; CGI), concurrent drugs, head circumference (HC) and inion-nasion distance (IND). Age, IND and CGI severity predicted seizure threshold in forward, stepwise, linear regression model.
ECT 发作阈值的决定因素研究不足。鉴于 ECT 人群和混杂因素的差异，有必要在我们的人群中进行研究。班加罗尔国家心理健康和神经科学研究所的治疗精神科医生推荐的连续同意住院患者（N=100）作为本研究的样本。硫喷妥钠、琥珀酰胆碱和阿托品用于改良。在第一次 ECT 时通过滴定法确定发作阈值（因变量）。独立变量为年龄、性别、诊断、疾病严重程度（临床总体印象；CGI）、同时使用的药物、头围（HC）和鼻根颏下距离（IND）。年龄、IND 和 CGI 严重程度在正向、逐步、线性回归模型中预测了发作阈值。
