Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee, -247667, Uttrakhand, India.
Dalton Trans. 2011 Jul 21;40(27):7077-121. doi: 10.1039/c0dt01426e. Epub 2011 Apr 14.
Schiff bases are the most widely used versatile ligands, able to coordinate many elements and to stabilize them in various oxidation states. Recently, this class of compounds has been employed as models for biological systems, and in control of stereochemistry in six-coordinate transition metal complexes. Recently, the chemistry of organotin(IV) complexes of Schiff bases has also stemmed from their antitumour, antimicrobial, antinematicidal, anti-insecticidal and anti-inflammatory activities. Furthermore, organotin(IV) complexes of Schiff bases present a wide variety of interesting structural possibilities. Both aliphatic and aromatic Schiff bases in their neutral and deprotonated forms have been used to yield adducts and chelates with variable stoichiometry and different modes of coordination. This critical review (>155 references) focuses upon the chemistry and biological applications of organotin(IV) complexes of Schiff bases reported in the past 15 years. Thermal behavior of these complexes is also discussed.
席夫碱是应用最广泛的多功能配体，能够与许多元素配位，并稳定它们的各种氧化态。最近，这类化合物被用作生物体系的模型，并用于控制六配位过渡金属配合物的立体化学。最近，席夫碱的有机锡（IV）配合物的化学性质也源于其抗肿瘤、抗微生物、抗线虫、抗昆虫和抗炎活性。此外，席夫碱的有机锡（IV）配合物呈现出多种多样有趣的结构可能性。脂肪族和芳香族的席夫碱以中性和去质子化形式被用于生成加合物和螯合物，具有可变的化学计量和不同的配位方式。本综述（>155 篇参考文献）重点介绍了过去 15 年报道的席夫碱的有机锡（IV）配合物的化学和生物应用。还讨论了这些配合物的热行为。
