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巴基斯坦的疟疾控制:新工具在手,但面临挑战的流行病学现实。

Malaria control in Pakistan: new tools at hand but challenging epidemiological realities.

机构信息

World Health Organization, Country Office, Islamabad, Pakistan.

出版信息

East Mediterr Health J. 2010;16 Suppl:S54-60.

PMID:21495589
Abstract

Malaria is endemic in Pakistan and constitutes a national health priority. However the parasite and vectors are showing resistance to common antimalarial drugs and insecticides. The provinces of Balochistan, Sindh and Khyber Pakhtunkhwa and the Federally Administered Tribal Areas have the highest malaria burden. Districts and agencies bordering Afghanistan and Islamic Republic of Iran account for 37% of the malaria burden with an annual parasite incidence (API) exceeding 4.5/1000 population per year. Moreover, there has been a growing risk of Plasmodium falciparum malaria incidence in areas where previously P. vivax was predominant. New and effective control tools have been introduced such as rapid diagnostic tests, artemisinin-based combination therapy and long-lasting insecticide-treated nets. This paper reports the progress achieved in the implementation of a malaria control strategy in Pakistan, shares major outstanding challenges and unearths the potential of performance-based implementation for advancing resource mobilization and collaborative partnerships.

摘要

疟疾在巴基斯坦流行,是该国的一项重点卫生问题。然而,寄生虫和传播媒介对常用抗疟药物和杀虫剂表现出了耐药性。俾路支省、信德省、开伯尔-普赫图赫瓦省和联邦直辖部落地区的疟疾负担最重。与阿富汗和伊朗伊斯兰共和国接壤的地区占疟疾负担的 37%,每年的寄生虫发病率(API)超过 4.5/1000 人。此外,以前以间日疟原虫为主的地区,恶性疟原虫疟疾的发病率也在不断上升。快速诊断检测、青蒿素为基础的联合疗法和长效驱虫蚊帐等新的有效控制工具已经推出。本文报告了在巴基斯坦实施疟疾控制策略方面所取得的进展,分享了主要的突出挑战,并探讨了基于绩效的实施在推动资源调动和合作伙伴关系方面的潜力。

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