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一只大猩猩感染巴拉姆希阿米巴原虫致死——德国首例巴拉姆希阿米巴病病例

Fatal Balamuthia mandrillaris infection in a gorilla - first case of balamuthiasis in Germany.

作者信息

Mätz-Rensing Kerstin, Kunze Marius, Zöller Martina, Roos Christian, Kiderlen Albrecht F, Ludwig Carsten, Kaup Franz-Josef

机构信息

German Primate Center, Göttingen, Germany.

出版信息

J Med Primatol. 2011 Dec;40(6):437-40. doi: 10.1111/j.1600-0684.2011.00479.x. Epub 2011 Apr 18.

DOI:10.1111/j.1600-0684.2011.00479.x
PMID:21496054
Abstract

BACKGROUND

A 12-year-old female western lowland gorilla died in a zoological garden in Germany after exhibiting general neurological signs.

METHODS

Balamuthia mandrillaris was identified as causative agent by indirect immunofluorescent staining of brain sections and confirmed by PCR and respective sequencing.

RESULTS

The animal suffered from a chronic progressive necrotizing amebic meningoencephalitis.

CONCLUSION

This is the first case of Balamuthia amebic encephalitis in Germany.

摘要

背景

一只12岁的西部低地大猩猩在德国一家动物园出现全身神经症状后死亡。

方法

通过脑切片间接免疫荧光染色鉴定曼氏巴贝斯虫为病原体，并经聚合酶链反应（PCR）及相应测序证实。

结果

该动物患有慢性进行性坏死性阿米巴脑膜脑炎。

结论

这是德国首例巴贝斯虫性脑炎病例。

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