Department of Ophthalmology, Peterborough and Stamford Hospitals NHS Trust, Peterborough, UK.
Clin Dermatol. 2011 May-Jun;29(3):295-9. doi: 10.1016/j.clindermatol.2010.11.008.
Identifying contact allergens in ophthalmic medications can be a challenging and daunting experience. We summarize data on topical ophthalmic medications with the potential to cause periorbital contact dermatitis and allergic conjunctivitis, highlighting current dilemmas and controversies in this area. The following groups of allergens are reviewed: preservatives, antiglaucoma medications (prostaglandin analogues, β-blockers, carbonic anhydrase inhibitors, parasympathomimetics, sympathomimetics), antiinflammatory medications (nonsteroidal antiinflammatory drugs, corticosteroids), antibiotics, antivirals, antiallergic medications (antihistamines, cromones), anaesthetics, mydriatics, and cycloplegics.
识别眼部药物中的接触过敏原可能是一项具有挑战性和艰巨的任务。我们总结了具有引起眶周接触性皮炎和过敏性结膜炎潜力的局部眼部药物的数据，重点介绍了该领域当前的困境和争议。以下是审查的过敏原组：防腐剂、抗青光眼药物（前列腺素类似物、β 受体阻滞剂、碳酸酐酶抑制剂、拟副交感神经药、拟交感神经药）、抗炎药物（非甾体抗炎药、皮质类固醇）、抗生素、抗病毒药物、抗过敏药物（抗组胺药、克罗马宁）、麻醉剂、散瞳剂和睫状肌麻痹剂。
