Zhang Bin-Feng, Zhang Qiu-Ping, Liu Hai, Chou Gui-Xin, Wang Zheng-Tao
The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai 201210, China; Shanghai R&D Center for Standardization of Chinese Medicines, Shanghai 201210, China.
The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai 201210, China; Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China.
Phytochemistry. 2011 Jun;72(9):916-22. doi: 10.1016/j.phytochem.2011.03.021. Epub 2011 Apr 16.
Six iridoids, geleganoids, designated A-F, and five iridoid glycosides, geleganosides A and B together with three previously reported compounds, were isolated from leaves of Gelsemium elegans. Their structures were elucidated by spectroscopic and chemical analyses. The relative configuration of geleganoid A was confirmed by X-ray crystallographic diffraction analysis, and the absolute configuration of geleganoid B was determined by a modified Mosher's method. Selected compounds were evaluated for PC12 cell neurite outgrowth activity, but they were inactive.
