McCown Jennifer L, Specht Andrew J
PETS Referral Center, Berkeley, CA, USA.
J Am Anim Hosp Assoc. 2011 May-Jun;47(3):151-60. doi: 10.5326/JAAHA-MS-5553. Epub 2011 Apr 15.
Iron is an essential element for nearly all living organisms and disruption of iron homeostasis can lead to a number of clinical manifestations. Iron is used in the formation of both hemoglobin and myoglobin, as well as numerous enzyme systems of the body. Disorders of iron in the body include iron deficiency anemia, anemia of inflammatory disease, and iron overload. This article reviews normal iron metabolism, disease syndromes of iron imbalance, diagnostic testing, and treatment of either iron deficiency or excess. Recent advances in diagnosing iron deficiency using reticulocyte indices are reviewed.
铁是几乎所有生物的必需元素，铁稳态的破坏会导致多种临床表现。铁用于血红蛋白和肌红蛋白的形成，以及身体的众多酶系统。体内铁紊乱包括缺铁性贫血、炎症性疾病贫血和铁过载。本文综述了正常铁代谢、铁失衡的疾病综合征、诊断检测以及缺铁或铁过量的治疗。还综述了使用网织红细胞指数诊断缺铁的最新进展。
