Faculté de pharmacie, Université Laval, Québec.
Can Respir J. 2011 Mar-Apr;18(2):97-104. doi: 10.1155/2011/426528.
When used properly, asthma drugs can reduce asthma-related morbidity and mortality.
To assess the use of asthma drugs, and to identify factors associated with appropriateness of use among patients 12 to 45 years of age.
Asthmatic patients were interviewed about their asthma drug(s) use and the factors potentially associated with appropriateness of use according to the 2003 Canadian Asthma Consensus Conference guidelines. To determine the factors associated with the appropriate use of asthma drugs, a multivariate logistic regression model was built using a stepwise procedure, and ORs and associated 95% CIs were calculated.
Of the 349 study participants, 43 (12.3%) reported appropriate use of their asthma drugs. Respondents who were more likely to report appropriate use were patients with sound knowledge of their asthma drugs (OR 2.61 [95% CI 1.29 to 5.29]), those in good, very good or excellent self-perceived health (OR 3.37 [95% CI 1.31 to 8.71]), those who had consulted a specialist during the preceding year (OR 2.28 [95% CI 1.05 to 4.97]) and those who declared themselves short of drugs due to a lack of money (OR 2.78 [95% CI 1.26 to 6.17]).
Results of the present study suggested that recommendations in the current guidelines regarding the appropriate use of asthma medications are being poorly implemented. Educational interventions with the aim of improving quality of care and knowledge about asthma drugs should be offered.
如果使用得当,哮喘药物可以降低与哮喘相关的发病率和死亡率。
评估哮喘药物的使用情况,并确定与 12 至 45 岁患者使用药物的适当性相关的因素。
根据 2003 年加拿大哮喘共识会议指南,对哮喘患者进行访谈,了解他们的哮喘药物使用情况以及与使用适当性相关的潜在因素。为了确定与哮喘药物适当使用相关的因素,使用逐步程序构建了多变量逻辑回归模型,并计算了 OR 和相关的 95%CI。
在 349 名研究参与者中,有 43 人(12.3%)报告了他们的哮喘药物使用适当。更有可能报告适当使用的受访者是对哮喘药物有良好了解的患者(OR 2.61 [95%CI 1.29 至 5.29])、自我感知健康状况良好、非常好或极好的患者(OR 3.37 [95%CI 1.31 至 8.71])、在过去一年中咨询过专家的患者(OR 2.28 [95%CI 1.05 至 4.97])和因资金不足而表示药物短缺的患者(OR 2.78 [95%CI 1.26 至 6.17])。
本研究结果表明,目前指南中关于哮喘药物适当使用的建议实施情况不佳。应提供旨在改善护理质量和哮喘药物知识的教育干预措施。