Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Behav Brain Res. 2011 Sep 30;223(1):48-52. doi: 10.1016/j.bbr.2011.03.071. Epub 2011 Apr 8.
Synesthesia is a perceptual condition in which sensory stimulation triggers anomalous sensory experiences. In colored sequence synesthesia (CSS), color experiences are triggered by sequences such as letters or numbers. We performed a family based linkage analysis to identify genetic loci responsible for the increased neural crosstalk underlying CSS. Our results implicate a 23 MB region at 16q12.2-23.1, providing the first step in understanding the molecular basis of CSS.
联觉是一种感知状态,其中感官刺激会引发异常的感官体验。在彩色序列联觉(CSS)中,颜色体验会被字母或数字等序列触发。我们进行了一项基于家族的连锁分析,以确定导致 CSS 背后的神经串扰增加的遗传基因座。我们的结果表明,在 16q12.2-23.1 处存在一个 23MB 的区域,这为理解 CSS 的分子基础迈出了第一步。