Sun S M
Department of Ophthalmology, First Hospital, Beijing Medical University.
Zhonghua Yan Ke Za Zhi. 1990 Sep;26(5):258-60.
37 (37%) of 100 patients with anterior uveitis were found HLA-B27 positive (5.3% in the normal controls); 35 (94.6%) of the 37 cases were nongranulomatous and 78.0% were associated with various types of arthritis. T-cell subsets in periphery circulation were evaluated in 47 anterior uveitis patients and 18 controls by means of monoclonal antibodies. Patients with active anterior uveitis had less OKT3+ cells than patients in the inactive phase; there were more OKT4+ and OKT8+ cells in patients in the active phase than in the controls, and particularly the OKT8+ cells were more than in patients of the inactive phase. The mean OKT4+/OKT8+ ratio was not significantly different from that of the controls; however, values of the OKT4+/OKT8+ ratio were abnormal in some patients, and there were more cases with lower ratio values in the active than in the inactive patients.
100例前葡萄膜炎患者中有37例（37%）HLA - B27呈阳性（正常对照组中为5.3%）；37例中的35例（94.6%）为非肉芽肿性，且78.0%与各种类型的关节炎相关。采用单克隆抗体对47例前葡萄膜炎患者和18例对照者的外周血T细胞亚群进行了评估。活动期前葡萄膜炎患者的OKT3 +细胞比非活动期患者少；活动期患者的OKT4 +和OKT8 +细胞比对照组多，尤其是OKT8 +细胞比非活动期患者多。OKT4 + /OKT8 +比值的平均值与对照组无显著差异；然而，部分患者的OKT4 + /OKT8 +比值异常，且活动期患者中该比值较低的病例比非活动期患者更多。
