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本文引用的文献

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LEEways: tales of EPEC, ATEC and EHEC.LEEways：EPEC、ATEC 和 EHEC 的故事。
Cell Microbiol. 2010 Nov;12(11):1544-52. doi: 10.1111/j.1462-5822.2010.01518.x. Epub 2010 Aug 31.
2
Comparative analysis of the locus of enterocyte effacement and its flanking regions.肠上皮细胞脱落位点及其侧翼区域的比较分析。
Infect Immun. 2009 Aug;77(8):3501-13. doi: 10.1128/IAI.00090-09. Epub 2009 Jun 8.
3
Identification and characterization of Ibe, a novel type III effector protein of A/E pathogens targeting human IQGAP1.鉴定与表征Ibe，一种靶向人类IQGAP1的A/E病原体新型III型效应蛋白。
Cell Microbiol. 2009 Apr;11(4):661-77. doi: 10.1111/j.1462-5822.2009.01284.x. Epub 2009 Jan 7.
4
Shiga toxin-negative attaching and effacing Escherichia coli: distinct clinical associations with bacterial phylogeny and virulence traits and inferred in-host pathogen evolution.志贺毒素阴性紧密黏附并损伤肠上皮的大肠杆菌：与细菌系统发育和毒力特征的不同临床关联以及推断的宿主体内病原体进化
Clin Infect Dis. 2008 Jul 15;47(2):208-17. doi: 10.1086/589245.
5
Identification of unconventional intestinal pathogenic Escherichia coli isolates expressing intermediate virulence factor profiles by using a novel single-step multiplex PCR.通过使用新型单步多重PCR鉴定表达中等毒力因子谱的非常规肠道致病性大肠杆菌分离株。
Appl Environ Microbiol. 2007 May;73(10):3380-90. doi: 10.1128/AEM.02855-06. Epub 2007 Mar 30.
6
Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome.产志贺毒素大肠杆菌与溶血尿毒综合征
Lancet. 2005;365(9464):1073-86. doi: 10.1016/S0140-6736(05)71144-2.
7
Emerging enteropathogenic Escherichia coli strains?
Emerg Infect Dis. 2004 Oct;10(10):1851-5. doi: 10.3201/eid1010.031093.
8
Molecular analysis of cytolysin A (ClyA) in pathogenic Escherichia coli strains.致病性大肠杆菌菌株中细胞溶素A（ClyA）的分子分析
J Bacteriol. 2004 Aug;186(16):5311-20. doi: 10.1128/JB.186.16.5311-5320.2004.
9
Pathogenic Escherichia coli.致病性大肠杆菌
Nat Rev Microbiol. 2004 Feb;2(2):123-40. doi: 10.1038/nrmicro818.
10
eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data.eBURST：从多位点序列分型数据推断相关细菌基因型簇之间的进化谱系模式。
J Bacteriol. 2004 Mar;186(5):1518-30. doi: 10.1128/JB.186.5.1518-1530.2004.

巴西圣保罗腹泻患者分离的大肠杆菌菌株的特征：多重 PCR 鉴定中间毒力因子谱。

Characterization of Escherichia coli strains isolated from patients with diarrhea in Sao Paulo, Brazil: identification of intermediate virulence factor profiles by multiplex PCR.

机构信息

Institut für Infektiologie, Zentrum für Molekularbiologie der Entzündung, Von Esmarch Str 56, D-48149 Münster, Germany.

出版信息

J Clin Microbiol. 2011 Jun;49(6):2274-8. doi: 10.1128/JCM.00386-11. Epub 2011 Apr 20.

DOI:10.1128/JCM.00386-11
PMID:21508159
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3122764/
Abstract

Intestinal pathogenic Escherichia coli is a major causative agent of severe diarrhea. In this study the prevalences of different pathotypes among 702 E. coli isolates from Brazilian patients with diarrhea were determined by multiplex PCR. Interestingly, most strains were enteroaggregative E. coli (EAEC) strains, followed by atypical EPEC (ATEC) strains. Classical enteropathogenic E. coli (EPEC) strains were not detected.

摘要

肠致病性大肠杆菌是严重腹泻的主要病原体。在这项研究中，通过多重 PCR 方法检测了来自巴西腹泻患者的 702 株大肠杆菌分离株中不同血清型的流行情况。有趣的是，大多数菌株为聚集性肠产毒性大肠杆菌（EAEC）菌株，其次是非典型性肠致病性大肠杆菌（ATEC）菌株。未检测到经典肠致病性大肠杆菌（EPEC）菌株。