Jain Vanita Dharan, Sciscione Anthony
Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology, Delaware Center for Maternal Fetal Medicine, Christiana Hospital, Newark, Delaware, USA.
Clin Obstet Gynecol. 2011 Jun;54(2):351-7. doi: 10.1097/GRF.0b013e318217edaf.
Current management of preterm premature rupture of the membranes centers around the expectant management with antibiotics and steroid therapy. Membrane rupture seems to be the result of a mechanical event. Studying the physical properties of the membranes may help to gain understanding of the nature and causes of membrane rupture. This article reviews membrane mechanics, advances in membrane healing, and strategies in the prevention of membrane rupture. The physiologic mechanisms that lead to membrane rupture have not yet been fully elucidated. Models that test the biomechanics of the membranes should be used to develop strategies for repair or prevention.
目前，胎膜早破的管理主要围绕使用抗生素和类固醇疗法进行期待治疗。胎膜破裂似乎是机械性事件的结果。研究胎膜的物理特性可能有助于理解胎膜破裂的本质和原因。本文综述了胎膜力学、胎膜愈合方面的进展以及预防胎膜破裂的策略。导致胎膜破裂的生理机制尚未完全阐明。应使用测试胎膜生物力学的模型来制定修复或预防策略。
