Department of Neurology, Antwerp University Hospital, Edegem, Belgium.
Acta Neurol Belg. 2011 Mar;111(1):69-71.
We describe the case of a 36-year-old man presenting with cognitive impairment and personality change. General paresis of the insane, the chronic cerebral parenchymatous form of neurosyphilis, was diagnosed. MRI showed the typical severe frontotemporal atrophy. Despite antibiotic treatment his mental state further declined. General paresis is rare and diagnosis is difficult because of the non-specific neuropsychiatric symptoms. Early diagnosis and treatment are important.
我们描述了一位 36 岁男性患者，表现为认知障碍和人格改变。诊断为麻痹性痴呆，即神经梅毒的慢性脑实质型。MRI 显示典型的严重额颞叶萎缩。尽管进行了抗生素治疗，但其精神状态仍进一步恶化。麻痹性痴呆较为罕见，由于其神经精神症状不具特异性，因此诊断较为困难。早期诊断和治疗非常重要。
