Programa de Pós-Graduação em Neurociências, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Bipolar Disord. 2012 May;14(3):309-12. doi: 10.1111/j.1399-5618.2012.01007.x.
General paresis of the insane is a late and severe form of neurosyphilis characterized by nonspecific neuropsychiatric symptoms. There are a limited number of case reports of mood disorders presenting in neurosyphilis, with depressive illness being the most common.
We performed a literature review of case reports of secondary bipolar disorder induced by syphilitic infection.
Herein reported is a case of a 53-year-old woman who initially presented with symptoms of mania and depression, mimicking bipolar disorder, but was subsequently diagnosed with general paresis of the insane.
The present case report emphasizes that if a substantial delay occurs in syphilis diagnosis and management, the patient may have a very poor prognosis.
精神错乱性麻痹是神经梅毒的一种晚期和严重形式，其特征为非特异性神经精神症状。神经梅毒中出现心境障碍的病例报告数量有限，其中最常见的是抑郁障碍。
我们对由梅毒感染引起的继发性双相障碍的病例报告进行了文献回顾。
本文报告了一例 53 岁女性，最初表现为躁狂和抑郁症状，类似于双相障碍，但随后被诊断为精神错乱性麻痹。
本病例报告强调，如果梅毒的诊断和治疗出现明显延迟，患者的预后可能非常差。
